ArticleNeural plasticity2019
Posttraining Alpha Transcranial Alternating Current Stimulation Impairs Motor Consolidation in Elderly People.
Article in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of transcranial alternating current stimulation on motor performance and motor learning for healthy individuals: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- A Systematic Review of Non-invasive Brain Stimulation Applications to Memory in Healthy Aging.Frontiers in neurology · 2020Pooled it
- Amplitude-modulated kilohertz stimulation targeting beta-band activity disrupts motor learning.bioRxiv : the preprint server for biology · 2026Article
- Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN).Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- 20 Hz tACS engages striatal THINs to enhance β-band synchrony and motor drive.Frontiers in neuroscience · 2026Article
- Variable E-field properties of dual-site tACS with phase lags.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Beta tACS of varying intensities differentially affect resting-state and movement-related sensorimotor power.Frontiers in neuroscience · 2025Article
- The Modulatory Effects of Transcranial Alternating Current Stimulation on Brain Oscillatory Patterns in the Beta Band in Healthy Older Adults.Brain sciences · 2024Article
- An overview of the effects and mechanisms of transcranial stimulation frequency on motor learning.Journal of neuroengineering and rehabilitation · 2024Review
- Beta tACS of varying intensities differentially affect resting-state and movement-related M1-M1 connectivity.Frontiers in neuroscience · 2024Article
- Attempting to counteract vigilance decrement in older adults with brain stimulation.Frontiers in neuroergonomics · 2023Article
- Narrative Review of Noninvasive Brain Stimulation in Stroke Rehabilitation.Medical science monitor : international medical journal of experimental and clinical research · 2022Review
- Motor Learning Based on Oscillatory Brain Activity Using Transcranial Alternating Current Stimulation: A Review.Brain sciences · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The retention of a new sequential motor skill relies on repeated practice and subsequent consolidation in the absence of active skill practice. While the early phase of skill acquisition remains relatively unaffected in older adults, posttraining consolidation appears to be selectively impaired by advancing age. Motor learning is associated with posttraining changes of oscillatory alpha and beta neuronal activities in the motor cortex. However, whether or not these oscillatory dynamics relate to posttraining consolidation and how they relate to the age-specific impairment of motor consolidation in older adults remains elusive. Transcranial alternating current stimulation (tACS) is a noninvasive brain stimulation technique capable of modulating such neuronal oscillations. Here, we examined whether tACS targeting M1 immediately following explicit motor sequence training is capable of modulating motor skill consolidation in older adults. In two sets of double-blind, sham-controlled experiments, tACS targeting left M1 was applied at either 10 Hz (alpha-tACS) or 20 Hz (beta-tACS) immediately after termination of a motor sequence training with the right (dominant) hand. Task performance was retested after an interval of 6 hours to assess consolidation of the training-acquired skill. EEG was recorded over left M1 to be able to detect local after-effects on oscillatory activity induced by tACS. Relative to the sham intervention, consolidation was selectively disrupted by posttraining alpha-tACS of M1, while posttraining beta-tACS of M1 had no effect on delayed retest performance compared to the sham intervention. No significant postinterventional changes of oscillatory activity in M1 were detected following alpha-tACS or beta-tACS. Our findings point to a frequency-specific interaction of tACS with posttraining motor memory processing and may suggest an inhibitory role of immediate posttraining alpha oscillations in M1 with respect to motor consolidation in healthy older adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.