ArticleFrontiers in physiology2019
Individually Rate Corrected QTc Intervals in Children and Adolescents.
Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Heart Rate Influences the Relationship Between Heart Rate Variability and Ventricular Repolarization in Children: A 24-h Holter Study.Journal of cardiovascular development and disease · 2026Article
- Direct evaluation of the electrocardiographic spatial QRS-T angle without the need for orthogonal transformation.Scientific reports · 2026Article
- QT interval changes in transgender/gender diverse adolescents receiving gonadotropin-releasing hormone agonist and gender-affirming hormonal treatment.International journal of transgender health · 2026Article
- Development of the Cardiovascular System During Adolescence.Advances in experimental medicine and biology · 2026Review
- Psychiatric Medications and QTc Prolongation in the Pediatric Population.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2025Article
- Prevalence of Electrocardiographic Changes and Risk Factors for QTc Prolongation Among Steady State Sickle Cell Disease Patients: Cooperative Study of Sickle Cell Disease.Oman medical journal · 2025Article
- QTc Interval Prolongation and Its Association With Electrolyte Abnormalities and Psychotropic Drug Use Among Patients With Eating Disorders.CJC pediatric and congenital heart disease · 2024Article
- Effects of Sex on the Susceptibility for Atrial Fibrillation in Pigs with Ischemic Heart Failure.Cells · 2023Article
- QTc prolongation in adolescents with acute alcohol intoxication.European journal of pediatrics · 2022Observational
- The best QT correction formula in a non-hospitalized population: the Fasa PERSIAN cohort study.BMC cardiovascular disorders · 2022Article
- Intra-subject stability of different expressions of spatial QRS-T angle and their relationship to heart rate.Frontiers in physiology · 2022Article
- Spatial distribution of physiologic 12-lead QRS complex.Scientific reports · 2021Article
- Sex and Rate Change Differences in QT/RR Hysteresis in Healthy Subjects.Frontiers in physiology · 2021Article
- Problems with Bazett QTc correction in paediatric screening of prolonged QTc interval.BMC pediatrics · 2020Article
- Physiologic heart rate dependency of the PQ interval and its sex differences.Scientific reports · 2020Article
- The impact of age on long QT syndrome.Aging · 2019Article
- Sex differences in heart rate responses to postural provocations.International journal of cardiology · 2019Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate evaluation of the appearance of QTc sex differences during childhood and adolescence is intricate. Inter-subject differences of individual QT/RR patterns make generic heart rate corrections inaccurate because of fast resting heart rates in children. The study investigated 527 healthy children and adolescents aged 4-19 years (268 females, 50.9%). All underwent continuous ECG 12-lead monitoring while performing postural changes during a 70-min investigative protocol to obtain QT interval measurements at different heart rates. On average, more than 1200 ECG measurements (QT interval and its 5-min history of preceding RR intervals) were made in each subject. Curvilinear QT/RR regression involving intra-individual correction for QT/RR hysteresis were calculated in each subject. The projection of the QT/RR regressions to the heart rate of 60 beats per minute defined individually corrected QTc intervals. In males, gradual QTc shortening by about 15 ms appeared during the ages of 13-19 years synchronously with the incidence of secondary sex signs (
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