Evidence map›Paper›PMID 31427975›Full record

ArticleFrontiers in pharmacology2019

Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation

Hima Dhakal, Soyoung Lee, Eun-Nam Kim, Jin Kyeong Choi, Min-Jong Kim, Jinjoo Kang, Young-Ae Choi, Moon-Chang Baek, Byungheon Lee, Hyun-Shik Lee and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Regulation of mCell biology and toxicology · 2026
    Review
  4. Article
  5. Vinpocetine, a phosphodiesterase 1 inhibitor, mitigates atopic dermatitis-like skin inflammation.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  6. Ethanol Extract ofAdvances in pharmacological and pharmaceutical sciences · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Hima DhakalCell & Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, South Korea.
Soyoung LeeImmunoregulatory Materials Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, South Korea.
Eun-Nam KimCollege of Pharmacy, Keimyung University, Daegu, South Korea.
Jin Kyeong ChoiMolecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, United States.
Min-Jong KimDepartment of Pharmacology, School of Medicine, Kyungpook National University, Daegu, South Korea.
Jinjoo KangDepartment of Pharmacology, School of Medicine, Kyungpook National University, Daegu, South Korea.
Young-Ae ChoiDepartment of Pharmacology, School of Medicine, Kyungpook National University, Daegu, South Korea.
Moon-Chang BaekDepartment of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea.
Byungheon LeeDepartment of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu, South Korea.
Hyun-Shik LeeSchool of Life Sciences, Kyungpook National University, Daegu, South Korea.
Tae-Yong ShinCollege of Pharmacy, Woosuk University, Jeonju, South Korea.
Gil-Saeng JeongCollege of Pharmacy, Keimyung University, Daegu, South Korea.
Sang-Hyun KimCell & Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, South Korea.
Kyungpook National University · KRKeimyung University · KRKorea Research Institute of Bioscience and Biotechnology · KRNational Eye Institute · USWoosuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cells are effector cells that induce allergic inflammation by secreting inflammatory mediators. Gomisin M2 (G.M2) is a lignan isolated from

Indexed as

allergic inflammationanaphylaxiscalciumGomisin M2mast cells

Identifiers

PMID31427975
PMCPMC6688163
OpenAlexW2959628523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.