ArticleFrontiers in aging neuroscience2019
Sex and Age Dependencies of Aqueductal Cerebrospinal Fluid Dynamics Parameters in Healthy Subjects.
Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Cerebral Blood and Cerebrospinal Fluid Flow Dynamics in Endurance Athletes: Associations With Aortic Recoil and Heart Rate.Scandinavian journal of medicine & science in sports · 2026Article
- Transient acute neuronal activation response caused by high concentrations of oligonucleotides in the cerebral spinal fluid.Nucleic acids research · 2026Article
- Subject-specific variability in cerebrospinal fluid flow characteristics through cerebral aqueducts in a healthy population: a magnetic resonance imaging and computational investigation.Medical & biological engineering & computing · 2025Article
- Choroid plexus-mediated CSF secretion remains stable in aging rats via high and age-resistant metabolic activity.Nature communications · 2025Article
- The Cerebrospinal Fluid Secretion Rate Increases in Awake and Freely Moving Rats but Differs With Experimental Methodology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Transmantle pressure under the influence of free breathing: non-invasive quantification of the aqueduct pressure gradient in healthy adults.Fluids and barriers of the CNS · 2025Article
- Quantitative evaluation of normal cerebrospinal fluid flow in Sylvian aqueduct and perivascular spaces of middle cerebral artery and circle of Willis using 2D phase-contrast MRI imaging.Frontiers in neuroscience · 2025Article
- Arterial and venous flow dynamics are modified by age in the non-human primate.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Numerical study of the effects of minor structures and mean velocity fields in the cerebrospinal fluid flow.Fluids and barriers of the CNS · 2024Article
- Quantifying CSF Dynamics disruption in idiopathic normal pressure hydrocephalus using phase lag between transmantle pressure and volumetric flow rate.Brain multiphysics · 2024Article
- Creating a Foundation for the Visualization of Intracranial Cerebrospinal Fluid Using Photon-Counting Technology in Spectral Imaging for Cranial CT.Diagnostics (Basel, Switzerland) · 2024Article
- Significant individual variation in cardiac-cycle-linked cerebrospinal fluid production following subarachnoid hemorrhage.Fluids and barriers of the CNS · 2024Article
- CSF and venous blood flow from childhood to adulthood studied by real-time phase-contrast MRI.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Cerebrospinal Fluid Flow Parameters in Normal Subjects above 40 Years of Age.The Indian journal of radiology & imaging · 2024Article
- Influence of age on the relation between body position and noninvasively acquired intracranial pulse waves.Scientific reports · 2024Article
- Sex Differences under Vitamin D Supplementation in an Animal Model of Progressive Multiple Sclerosis.Nutrients · 2024Article
- Pulsatility analysis of the circle of Willis.Aging brain · 2024Article
- Cerebrospinal Fluid Flow in Patients with Huntington's Disease.Annals of neurology · 2023Article
- Mechanisms of cerebrospinal fluid and brain interstitial fluid production.Neurobiology of disease · 2023Review
- Arterial spin labeling signal in the CSF: Implications for partial volume correction and blood-CSF barrier characterization.NMR in biomedicine · 2023Article
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Authors and funding
9 authors.
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Abstract
objectivesTo assess the influence of age and sex on 10 cerebrospinal fluid (CSF) flow dynamics parameters measured with an MR phase contrast (PC) sequence within the cerebral aqueduct at the level of the intercollicular sulcus. MATERIALS AND
methods128 healthy subjects (66 female subjects with a mean age of 52.9 years and 62 male subjects with a mean age of 51.8 years) with a normal Evans index, normal medial temporal atrophy (MTA) score, and without known disorders of the CSF circulation were included in the study. A PC MR sequence on a 3T MR scanner was used. Ten different flow parameters were analyzed using postprocessing software. Ordinal and linear regression models were calculated.
resultsThe parameters stroke volume (sex:
conclusionCSF flow dynamics parameters measured in the cerebral aqueduct are partly age and sex dependent. For establishment of reliable reference values for clinical use in future studies, the impact of sex and age should be considered and incorporated.
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