Evidence map›Paper›PMID 31427886›Full record

ArticleMediators of inflammation2019

Combined Exposure of Activated Intestinal Epithelial Cells to Nondigestible Oligosaccharides and CpG-ODN Suppresses Th2-Associated CCL22 Release While Enhancing Galectin-9, TGF

Saskia A Overbeek, Atanaska I Kostadinova, Martine A Boks, Simone M Hayen, Wilco de Jager, Belinda Van't Land, Leon M Knippels, Johan Garssen, Linette E M Willemsen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Saskia A OverbeekDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands.ORCID https://orcid.org/0000-0001-8107-6514
Atanaska I KostadinovaDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Martine A BoksMolecular Cell Biology and Immunology, VU University Medical Center (VUmc), Amsterdam, Netherlands.
Simone M HayenDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Wilco de JagerDepartment of Pediatric Immunology, Laboratory for Translational Immunology, University Medical Centre Utrecht, Utrecht, Netherlands.
Belinda Van't LandDepartment of Immunology, Danone Nutricia Research B.V., Utrecht, Netherlands.
Leon M KnippelsDepartment of Immunology, Danone Nutricia Research B.V., Utrecht, Netherlands.ORCID https://orcid.org/0000-0001-6572-6724
Johan GarssenDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Linette E M WillemsenDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands.ORCID https://orcid.org/0000-0001-9882-5331
Utrecht University · NLUniversity Medical Center Utrecht · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLDanone (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundShort-chain galacto- and long-chain fructo-oligosaccharides (scGOS/lcFOS) and CpG-ODN affect intestinal epithelial cells (IEC). Epithelial IL1

methodsSolid phase or transwell cultured IEC were preincubated with IL1

resultsIL1

conclusionIL1

Indexed as

CD4-Positive T-LymphocytesCells, CulturedGalectinsHT29 CellsHumansLymphocyte Culture Test, MixedOligosaccharidesTh1 CellsTransforming Growth Factor betaGalectinsLGALS9 protein, humanOligosaccharidesTransforming Growth Factor beta

Identifiers

PMID31427886
PMCPMC6683774
OpenAlexW2962784215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.