Evidence map›Paper›PMID 31427869›Full record

Trial reportJournal of sports science & medicine2019

Effects of Blood Flow Restriction Training with Protein Supplementation on Muscle Mass And Strength in Older Men.

Christoph Centner, Denise Zdzieblik, Llion Roberts, Albert Gollhofer, Daniel König

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC
In one paragraph

Trial report in Journal of sports science & medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 6 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 6 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Christoph CentnerDepartment of Sport and Sport Science, University of Freiburg, Freiburg, Germany.
Denise ZdzieblikDepartment of Sport and Sport Science, University of Freiburg, Freiburg, Germany.
Llion RobertsSchool of Allied Health Sciences, Griffith University, Gold Coast, Australia.
Albert GollhoferDepartment of Sport and Sport Science, University of Freiburg, Freiburg, Germany.
Daniel KönigDepartment of Sport and Sport Science, University of Freiburg, Freiburg, Germany.
University of Freiburg · DEGriffith University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood flow restriction (BFR) training has been shown to induce favorable changes in muscle mass and strength with a considerably low training load (20 - 30% 1RM). However, it has never been evaluated if an additional post-exercise protein supplementation enhances the effects of this training regimen. Thirty healthy older men (60.1 ± 7.6 years) were enrolled in the 8-week intervention and randomly allocated to one of the following groups: low-load BFR training with protein (collagen hydrolysate) supplementation (BFR-CH), low-load BFR training with placebo (BFR-PLA), or a control group without training, but with protein supplementation (CON). Muscle cross-sectional area (CSA), muscle strength, circulating reactive oxygen species and IGF-1 were measured before and after the intervention. Muscle CSA increased in both BFR-CH and BFR-PLA groups by 6.7 ± 3.2 % (p < 0.001) and 5.7 ± 2.7 % (p < 0.001) respectively. No significant changes were observed in the CON group (1.1 ± 1.7 %, p = 0.124). Evaluation of isometric strength (p = 0.247), insulin-like growth factor 1 (p = 0.705) and the production of reactive oxygen species (p

Indexed as

Dietary SupplementsAdaptation, PhysiologicalAgedAge FactorsCollagenDietary ProteinsHumansInsulin-Like Growth Factor IMaleMiddle AgedMuscle, SkeletalMuscle StrengthProspective StudiesReactive Oxygen SpeciesRegional Blood FlowResistance TrainingCollagenDietary ProteinsIGF1 protein, humanInsulin-Like Growth Factor IReactive Oxygen SpeciesagingBlood flow restrictionmagnetic resonance imagingmuscular hypertrophyprotein supplementationsarcopenia

Identifiers

PMID31427869
PMCPMC6683630
OpenAlexW2955351378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.