Evidence map›Paper›PMID 31427693›Full record

ArticleScientific reports2019

The Low Toxicity of Graphene Quantum Dots is Reflected by Marginal Gene Expression Changes of Primary Human Hematopoietic Stem Cells.

Stefan Fasbender, Lisa Zimmermann, Ron-Patrick Cadeddu, Martina Luysberg, Bastian Moll, Christoph Janiak, Thomas Heinzel, Rainer Haas

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stefan FasbenderCondensed Matter Physics Laboratory, Heinrich-Heine-University, D-40204, Düsseldorf, Germany.ORCID http://orcid.org/0000-0003-3054-7720
Lisa ZimmermannCondensed Matter Physics Laboratory, Heinrich-Heine-University, D-40204, Düsseldorf, Germany.
Ron-Patrick CadedduDepartment of Haematology, Oncology and Clinical Immunology, Heinrich-Heine-University, D-40204, Düsseldorf, Germany.
Martina LuysbergErnst Ruska Centre, Jülich Research Centre, D-52425, Jülich, Germany.
Bastian MollInstitute for Inorganic Chemistry and Structural Chemistry, Heinrich-Heine-University, D-40204, Düsseldorf, Germany.
Christoph JaniakInstitute for Inorganic Chemistry and Structural Chemistry, Heinrich-Heine-University, D-40204, Düsseldorf, Germany.
Thomas HeinzelCondensed Matter Physics Laboratory, Heinrich-Heine-University, D-40204, Düsseldorf, Germany. Thomas.Heinzel@hhu.de.
Rainer HaasDepartment of Haematology, Oncology and Clinical Immunology, Heinrich-Heine-University, D-40204, Düsseldorf, Germany. Haas@med.uni-duesseldorf.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene quantum dots (GQDs) are a promising next generation nanomaterial with manifold biomedical applications. For real world applications, comprehensive studies on their influence on the functionality of primary human cells are mandatory. Here, we report the effects of GQDs on the transcriptome of CD34

Indexed as

Gene Expression RegulationGraphiteQuantum DotsAntigens, CD34ApoptosisBiocompatible MaterialsCell SurvivalGene Expression ProfilingHematopoietic Stem CellsHumansNanostructuresTranscriptomeAntigens, CD34Biocompatible MaterialsGraphite

Identifiers

PMID31427693
PMCPMC6700176

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.