Evidence map›Paper›PMID 31427685›Full record

ArticleScientific reports2019

The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome: A single-center experience.

Jamila Kremer, Mina Farag, Marcin Zaradzki, Gabor Szabó, Arjang Ruhparwar, Klaus Kallenbach, Matthias Karck, Rawa Arif

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jamila KremerMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Mina FaragMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Marcin ZaradzkiMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Gabor SzabóMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Arjang RuhparwarMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Klaus KallenbachMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Matthias KarckMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Rawa ArifMarfan Center University Hospital Heidelberg, Department of Cardiac Surgery, University Hospital Heidelberg, Heidelberg, Germany. rawa.arif@med.uni-heidelberg.de.
Heidelberg University · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valve-sparing aortic root replacement (VSARR) through reimplantation technique is widely regarded as optimal surgical approach for Marfan syndrome (MFS) patients. Perioperative and long-term data from all MFS patients undergoing VSARR using David's technique at our center from 2007-2018 were analyzed. We included 56 patients with a mean age of 32.3 ± 12.3 years. Logistic EuroSCORE was 7.96 ± 5.2. Among others concomitant surgical procedures included aortic arch surgery (8.9%), mitral valve repair (23.2%) and replacement (1.7%). There were no operative deaths, nor in-hospital-mortality. One patient underwent re-exploration for bleeding, dialysis and pacemaker implantation was required in one case each. There was no occurrence of low-output syndrome nor neurological complications. Significant gender differences were not found, except for intraoperative blood transfusion occurring significantly more often in the female gender (p = 0.009). Despite significantly longer procedural times, concomitant surgery did not negatively impact overall outcome. Freedom of reoperation of the aortic root was 100% at 1 year, 97.7% at 8 years. Until last follow-up (61 ± 38 month) all patients survived, with no evidence of endocarditis. We emphasize once more that VSARR using David's procedure is a safe method for MFS patients with excellent long-term results even if concomitant procedures are performed.

Indexed as

AdolescentAdultAortaAortic Valve InsufficiencyBlood Vessel Prosthesis ImplantationChildDilatation, PathologicFemaleFollow-Up StudiesHumansMaleMarfan SyndromeMiddle AgedSeverity of Illness IndexTreatment OutcomeYoung Adult

Identifiers

PMID31427685
PMCPMC6700152
OpenAlexW2969701400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.