Evidence map›Paper›PMID 31427628›Full record

Trial reportScientific reports2019

Regular exercise improves asthma control in adults: A randomized controlled trial.

Jouni J K Jaakkola, Sirpa A M Aalto, Samu Hernberg, Simo-Pekka Kiihamäki, Maritta S Jaakkola

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Pulmonary rehabilitation versus usual care for adults with asthma.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Pooled it
  4. Trial
  5. Effect of combined strength and endurance training in adults with asthma: a randomized controlled trial.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Trial
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Association of daily steps over time with adult asthma incidence.The Journal of allergy and clinical immunology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Exercise Rehabilitation and Chronic Respiratory Diseases: Effects, Mechanisms, and Therapeutic Benefits.International journal of chronic obstructive pulmonary disease · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jouni J K JaakkolaCenter for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland. jouni.jaakkola@oulu.fi.ORCID http://orcid.org/0000-0003-4168-4683
Sirpa A M AaltoCenter for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Samu HernbergCenter for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Simo-Pekka KiihamäkiCenter for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Maritta S JaakkolaCenter for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Oulu University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a randomized controlled trial to test the hypothesis that a 24-week exercise intervention improves asthma control in adults. Adults with mild or moderate asthma were randomly assigned to either the exercise intervention group (IG) or the reference group (RG). Participants in IG received an individualized exercising program, including aerobic exercise at least three times a week for ≥30 minutes, muscle training, and stretching. The primary outcome was asthma control, measured by Asthma Control Test (ACT), asthma-related symptoms, and peak expiratory flow (PEF) variability. We estimated the risk (i.e. probability) of improvement in asthma control and the risk difference (RD) between IG and RG. Of 131 subjects (67 IG/64 RG) entered, 105 subjects (51/54) completed the trial (80%), and 89 (44/45) were analysed (68%). The ACT became better among 26 (62%) participants in IG and among 17 (39%) participants in RG. The effect of intervention on improving asthma control was 23% (RD = 0.23, 95% CI 0.027-0.438; P = 0.0320). The intervention also reduced shortness of breath by 30.1% (RD = 0.301, 95% CI 0.109-0.492; P = 0.003). The change in PEF variability was similar in both groups. Regular exercise improves asthma control measured by the ACT, while has little effect on PEF variability.

Indexed as

Physical Therapy ModalitiesAdolescentAdultAgedAsthmaDisease ProgressionExerciseFemaleHumansMaleMiddle AgedPeak Expiratory Flow RateQuality of LifeRespiratory Function TestsYoung Adult

Identifiers

PMID31427628
PMCPMC6700123
OpenAlexW2967824365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.