ArticleNature communications2019
IP
Abstract read
In one paragraph
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
178citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
178 citing papers in PubMed, 1 synthesis or guideline pooled it.
- MAM kinases: physiological roles, related diseases, and therapeutic perspectives-a systematic review.Cellular & molecular biology letters · 2025Pooled it
- Calcium overload-induced apoptosis in cancer cells: ER-mitochondria crosstalk and therapeutic implications.Pharmaceutical science advances · 2026Review
- Subcellular regulation of ferroptosis: roles of individual intracellular organelles and cross talk.American journal of physiology. Cell physiology · 2026Review
- Inter-Organelle Membrane Contact Sites as Physiological Regulatory Hubs in the Brain: From Neurons to Glial Cells.Biomolecules · 2026Review
- A conserved VPS34-PIKfyve-TRPML1-myosin II axis regulates the speed of amoeboid cell migration.EMBO reports · 2026Article
- IP3R2-mediated inter-organelle calcium signaling suppresses melanosome degradation.PLoS biology · 2026Article
- Intermembrane coupling between Bcl-xL and the IPCell reports · 2026Article
- Cryo-EM insights into isoform-specific properties of the IPNature communications · 2026Article
- Acute mitochondrial dysfunction impairs neuromuscular transmission and contractility in mouse diaphragm: the protective potential of 25-hydroxycholesterol.Journal of physiology and biochemistry · 2026Article
- Endothelial GDF15 deficiency enhances barrier function and mitigates pulmonary fibrosis.JCI insight · 2026Article
- Mitochondrial-endoplasmic reticulum interactions in lung diseases.Cell death & disease · 2026Review
- An INF2-dependent actin-mediated step in inositol 1,4,5-trisphosphate receptor cluster formation and activity.Current biology : CB · 2026Article
- Ameliorating calcium homeostasis improves longevity and healthspan in progeroid and naturally aged mice.Nature communications · 2026Article
- Huoxue Qianyang Qutan Recipe limits cardiac remodeling by regulating FUNDC1/IP3R2 signaling pathway in obese hypertensive rats.Scientific reports · 2026Article
- Holistic therapeutic philosophy: Boost a cascade communication between endoplasmic reticulum-mitochondria-lysosome to overload intracellular CaMaterials today. Bio · 2026Article
- A novel synthetic melanin as a potential anticancer agent that induces apoptosis and cyclin D downregulation through distinct pathways.The Journal of biological chemistry · 2026Article
- Mitochondria-ER contact sites (MERCS) in the cell cycle: molecular architecture and functional remodeling across cellular states.BMC biology · 2026Review
- The spatiotemporal dynamics of MAMs: mechanisms, pathologies, and therapeutic rewiring.Cellular & molecular biology letters · 2026Review
- Mitochondrial Calcium Signaling in Hepatocyte Health and Disease.Cold Spring Harbor perspectives in biology · 2026Review
- NUSAP1 Drives Endometrial Carcinoma via IP3R Phosphorylation, Calcium Dyshomeostasis, and ER-Stress-Mediated Apoptosis.ACS omega · 2026Article
118 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Adam BartokMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
David WeaverMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Tünde GolenárMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Zuzana NichtovaMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Máté KatonaMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Száva BánsághiMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Kamil J AlzayadyDepartment of Physiology and Pharmacology, University of Rochester, Rochester, NY, USA.
V Kaye ThomasDepartment of Physiology and Pharmacology, University of Rochester, Rochester, NY, USA.
Hideaki AndoLab for Developmental Neurobiology, RIKEN Brain Science Institute, Saitama, Japan.
Katsuhiko MikoshibaLab for Developmental Neurobiology, RIKEN Brain Science Institute, Saitama, Japan.
Suresh K JosephMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
David I YuleDepartment of Physiology and Pharmacology, University of Rochester, Rochester, NY, USA.
György CsordásMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA. gyorgy.csordas@jefferson.edu.
György HajnóczkyMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA. gyorgy.hajnoczky@jefferson.edu.ORCID http://orcid.org/0000-0003-3813-2570
Funding
[Ca2+]i and Secretory Dynamics in Parotid Acinar CellsR01DE014756 · NIDCR · UNIVERSITY OF ROCHESTER · PI David I Yule · 2002 to 2026
$9.9MMechanisms of Pulsatile Calcium SignalingR01DK051526 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY · 2001 to 2016
$4.3MMITOCHONDRIAL CALCIUM SIGNALING IN CELL DEATHR01GM059419 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY · 2000 to 2016
$4.0MMolecular Mechanisms of Mitochondrial Ca2+ TransportR01GM102724 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY · 2015 to 2020
$2.3MStudy of the mitochondrial-cellular response to environmental stress by flourescence imagingR33ES025672 · NIEHS · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, HAJNOCZKY, GYORGY · 2017 to 2019
$1.5MRedox Regulation of Intracellular Calcium SignalingR01DK103558 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY, JOSEPH, SURESH K · 2015 to 2018
$1.4MSTED3X Super Resolution Microscope for The University of Rochester and Western NY research communityS10OD023440 · OD · UNIVERSITY OF ROCHESTER · PI YULE, DAVID I · 2018 to 2018
$600kStudy of the mitochondrial-cellular response to environmental stress by flourescence imagingR21ES025672 · NIEHS · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, HAJNOCZKY, GYORGY · 2015 to 2016
$423k[Ca2+]i and Secretory Dynamics in Parotid Acinar CellsR56DE014756 · NIDCR · UNIVERSITY OF ROCHESTER · PI YULE, DAVID I · 2007 to 2007
$395kMECHANISMS OF PULSATILE CALCIUM SIGNALINGR29DK051526 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY · 1996 to 2000
$121kNIDCR NIH HHS R01 DE014756NIDCR NIH HHS R56 DE014756NIDDK NIH HHS R01 DK051526NIDDK NIH HHS R01 DK103558NIDDK NIH HHS R29 DK051526NIEHS NIH HHS R21 ES025672NIEHS NIH HHS R33 ES025672NIGMS NIH HHS R01 GM059419NIGMS NIH HHS R01 GM102724NIH HHS S10 OD023440
Abstract
Contact sites of endoplasmic reticulum (ER) and mitochondria locally convey calcium signals between the IP
Indexed as
AnimalsCalcium ChannelsCalcium SignalingCell Line, TumorCell SurvivalChickensEndoplasmic ReticulumHeLa CellsHumansInositol 1,4,5-Trisphosphate ReceptorsMitochondriaProtein IsoformsCalcium ChannelsInositol 1,4,5-Trisphosphate Receptorsmitochondrial calcium uniporterProtein Isoforms
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.