ArticleProceedings of the National Academy of Sciences of the United States of America2019
Peroxidase evolution in white-rot fungi follows wood lignin evolution in plants.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 68 citations in OpenAlex.
- Adaptive evolution of Agaricomycetes laccases follows wood lignin diversification in plants.Applied and environmental microbiology · 2026Article
- Diversity of Aromatic Aldehyde Dehydrogenases in Ceriporiopsis subvermispora: Insights into Fungal Vanillin Metabolism.Applied biochemistry and biotechnology · 2026Article
- Cross-kingdom comparative genomics reveal the metabolic potential of fungi for lignin turnover in deadwood.Nature ecology & evolution · 2025Article
- Genome analysis of the esca-associated Basidiomycetes Fomitiporia mediterranea, Fomitiporia polymorpha, Inonotus vitis, and Tropicoporus texanus reveals virulence factor repertoires characteristic of white-rot fungi.G3 (Bethesda, Md.) · 2024Article
- Structure-function characterization of two enzymes from novel subfamilies of manganese peroxidases secreted by the lignocellulose-degrading Agaricales fungi Agrocybe pediades and Cyathus striatus.Biotechnology for biofuels and bioproducts · 2024Article
- Unraveling the roles of coastal bacterial consortia in degradation of various lignocellulosic substrates.mSystems · 2023Article
- Molecular insights into the evolution of woody plant decay in the gut of termites.Science advances · 2023Article
- Visible light-exposed lignin facilitates cellulose solubilization by lytic polysaccharide monooxygenases.Nature communications · 2023Article
- Tree mycorrhizal association types control biodiversity-productivity relationship in a subtropical forest.Science advances · 2023Article
- Evaluation of the lignocellulose degradation potential of Mediterranean forests soil microbial communities through diversity and targeted functional metagenomics.Frontiers in microbiology · 2023Article
- Press water from the mechanical drying of Douglas-fir wood chips has multiple beneficial effects on lignocellulolytic fungi.Fungal biology and biotechnology · 2022Article
- Microbial consortium composed of Cellulomonas ZJW-6 and Acinetobacter DA-25 improves straw lignocellulose degradation.Archives of microbiology · 2022Article
- Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi.Frontiers in fungal biology · 2022Review
- Agaricales Mushroom Lignin Peroxidase: From Structure-Function to Degradative Capabilities.Antioxidants (Basel, Switzerland) · 2021Article
- Setting the stage for evolution of a new enzyme.Current opinion in structural biology · 2021Review
- Characterization of a Dye-Decolorizing Peroxidase fromJournal of fungi (Basel, Switzerland) · 2021Article
- Genomic Analysis Enlightens Agaricales Lifestyle Evolution and Increasing Peroxidase Diversity.Molecular biology and evolution · 2021Article
- Comparing Ligninolytic Capabilities of Bacterial and Fungal Dye-Decolorizing Peroxidases and Class-II Peroxidase-Catalases.International journal of molecular sciences · 2021Article
- Hallmarks of Basidiomycete Soft- and White-Rot in Wood-Decay -Omics Data of TwoMicroorganisms · 2021Article
- Uncovering the hidden diversity of litter-decomposition mechanisms in mushroom-forming fungi.The ISME journal · 2020Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A comparison of sequenced Agaricomycotina genomes suggests that efficient degradation of wood lignin was associated with the appearance of secreted peroxidases with a solvent-exposed catalytic tryptophan. This hypothesis is experimentally demonstrated here by resurrecting ancestral fungal peroxidases, after sequence reconstruction from genomes of extant white-rot Polyporales, and evaluating their oxidative attack on the lignin polymer by state-of-the-art analytical techniques. Rapid stopped-flow estimation of the transient-state constants for the 2 successive one-electron transfers from lignin to the peroxide-activated enzyme (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.