Evidence map›Paper›PMID 31427451›Full record

ArticleInfection and immunity2019

Discovery and Contribution of Nontypeable Haemophilus influenzae NTHI1441 to Human Respiratory Epithelial Cell Invasion.

C P Ahearn, C Kirkham, L D Chaves, Y Kong, M M Pettigrew, T F Murphy

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Thiooxazole Formation on a NontypeablebioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Copper-chelating natural products.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Review
  6. Inflammatory Responses to Non-TypeablePathogens (Basel, Switzerland) · 2025
    Article
  7. A multi-iron enzyme installs copper-binding oxazolone/thioamide pairs on a nontypeableProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

C P AhearnDepartment of Microbiology and Immunology, University at Buffalo, the State University of New York, Buffalo, New York, USA.
C KirkhamClinical and Translational Research Center, University at Buffalo, the State University of New York, Buffalo, New York, USA.
L D ChavesDivision of Nephrology, Department of Medicine, University at Buffalo, the State University of New York, Buffalo, New York, USA.
Y KongDepartment of Biostatistics, Yale School of Public Health, Yale University, New Haven, Connecticut, USA.
M M PettigrewDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, Connecticut, USA.
T F MurphyDepartment of Microbiology and Immunology, University at Buffalo, the State University of New York, Buffalo, New York, USA murphyt@buffalo.edu.
University at Buffalo, State University of New York · USYale University · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Persistent H. influenzae in COPD - virulence, vaccines and antibiotic resistanceR01AI019641 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 1985 to 2023
$7.9M
NCATS NIH HHS UL1 TR001412NIAID NIH HHS R01 AI019641
6 · The paper itself

Abstract

Nontypeable

Indexed as

Bacterial AdhesionBacterial ProteinsCloning, MolecularDNA, BacterialDNA, RecombinantEpithelial CellsGene DeletionGene Expression Regulation, BacterialGenome, BacterialHaemophilus InfectionsHaemophilus influenzaeHumansPulmonary Disease, Chronic ObstructiveRespiratory MucosaBacterial ProteinsDNA, BacterialDNA, Recombinantcell invasionCOPDhost-microbe interactioninvasinNTHipersistencevirulence

Identifiers

PMID31427451
PMCPMC6803334
OpenAlexW2969480681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.