Evidence map›Paper›PMID 31427427›Full record

ArticleJournal of cell science2019

Phosphorylation of connexin 43 at MAPK, PKC or CK1 sites each distinctly alter the kinetics of epidermal wound repair.

Kristin J Lastwika, Clarence A Dunn, Joell L Solan, Paul D Lampe

Open access · greenAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Cx45 regulation by kinases and impact of expression in heart failure.Journal of molecular and cellular cardiology · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. An Update on Connexin Gap Junction and Hemichannels in Diabetic Retinopathy.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kristin J LastwikaTranslational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center Seattle, WA 98109, USA.
Clarence A DunnTranslational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center Seattle, WA 98109, USA.
Joell L SolanTranslational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center Seattle, WA 98109, USA.
Paul D LampeTranslational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center Seattle, WA 98109, USA plampe@fredhutch.org.ORCID 0000-0002-1399-2761
Fred Hutch Cancer Center · US

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
PHOSPHORYLATION OF GAP JUNCTION PROTEINSR01GM055632 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LAMPE, PAUL D. · 1997 to 2017
$6.1M
NCI NIH HHS P30 CA015704NIGMS NIH HHS R01 GM055632
6 · The paper itself

Abstract

The gap junction protein connexin 43 (Cx43) is a key player in wound healing, and inhibitors of Cx43, which speed epidermal wound healing, are currently in clinical trials. Here, we provide direct

Indexed as

AnimalsCasein Kinase ICell LineConnexin 43DogsEpidermal CellsImmunohistochemistryKineticsMiceMitogen-Activated Protein KinasesPhosphorylationProtein Kinase CCasein Kinase IConnexin 43Mitogen-Activated Protein KinasesProtein Kinase CConnexin 43MigrationPhosphorylationWound healing

Identifiers

PMID31427427
PMCPMC6765181
OpenAlexW2969968611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.