Evidence map›Paper›PMID 31427393›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Acute Focal Seizures Start As Local Synchronizations of Neuronal Ensembles.

Michael Wenzel, Jordan P Hamm, Darcy S Peterka, Rafael Yuste

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
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  7. Downmodulation of Potassium Conductances Induces Epileptic Seizures in Cortical Network Models Via Multiple Synergistic Factors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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  12. Circuit Reorganization of Subicular Cell-Type-Specific Interneurons in Temporal Lobe Epilepsy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  13. Article
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  16. Review
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  18. Circumscribing Laser Cuts Attenuate Seizure Propagation in a Mouse Model of Focal Epilepsy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael WenzelNeurotechnology Center, Department of Biological Sciences, Columbia University, New York, New York 10027 michaelwenzel2946@gmail.com.
Jordan P HammNeurotechnology Center, Department of Biological Sciences, Columbia University, New York, New York 10027.
Darcy S PeterkaNeurotechnology Center, Department of Biological Sciences, Columbia University, New York, New York 10027.ORCID 0000-0001-7351-5820
Rafael YusteNeurotechnology Center, Department of Biological Sciences, Columbia University, New York, New York 10027.
Columbia University · US

Funding

IMAGING FUNCTIONAL CONNECTIVITY IN VISUAL CORTEXR01EY011787 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 1998 to 2021
$6.4M
Functional connectomics of the neocortical microcircuitDP1EY024503 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2013 to 2017
$4.0M
Effect of GABAergic inhibition of dendritic spines on synaptic pruning in the medial prefrontal cortex during adolescenceR01MH115900 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2019 to 2023
$3.2M
Functional consequences of GABAergic inhibition of dendritic spines at pubertyR01MH100561 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2013 to 2017
$3.0M
Two-photon optical control of astrocytic functionR01MH101218 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2013 to 2017
$2.0M
NEI NIH HHS DP1 EY024503NEI NIH HHS R01 EY011787NIMH NIH HHS R01 MH100561NIMH NIH HHS R01 MH101218NIMH NIH HHS R01 MH115900
6 · The paper itself

Abstract

Understanding seizure formation and spread remains a critical goal of epilepsy research. We used fast

Indexed as

AnimalsCalciumElectroencephalographyMaleMiceNeocortexNerve NetNeuronsSeizuresCalciumcalcium imagingepilepsyinterneuronsmicroseizuresseizurestwo-photon

Identifiers

PMID31427393
PMCPMC6807279
OpenAlexW2969325811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.