ArticleBMJ open2019
Variability in the burden of disease estimates with or without age weighting and discounting: a methodological study.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Indirect Costs of Non-Communicable Diseases within the Top Ten Causes of Mortality Worldwide: A Systematic Literature Review.Iranian journal of medical sciences · 2026Pooled it
- A systematic review of studies that estimated the burden of chronic non-communicable rare diseases using disability-adjusted life years.Orphanet journal of rare diseases · 2024Pooled it
- Disability-adjusted life years (DALYs) based COVID-19 health impact assessment: a systematic review.BMC public health · 2023Pooled it
- Burden of infectious disease studies in Europe and the United Kingdom: a review of methodological design choices.Epidemiology and infection · 2023Pooled it
- Trends, geographic distribution, and disease burden of bipolar disorder in Ecuador (2011-2021): An analysis of hospital discharge data.PloS one · 2025Observational
- Ethnodemographic characterization of stroke incidence and burden of disease in hospital discharge records in Ecuador.Frontiers in neurology · 2023Article
- Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010-2018.Tropical medicine and infectious disease · 2022Article
- Paediatric pneumonia research priorities in the context of COVID-19: A eDelphi study.Journal of global health · 2022Article
- Reflections on key methodological decisions in national burden of disease assessments.Archives of public health = Archives belges de sante publique · 2020Article
- Sexual Dysfunction Among Young Adults in Sweden-A Population-Based Observational Study.Sexual medicine · 2020Article
- Potential Years of Life Lost Due to COVID-19 in the United States, Italy, and Germany: An Old Formula with Newer Ideas.International journal of environmental research and public health · 2020Article
- Assessing the burden and spatial distribution of Taenia solium human neurocysticercosis in Ecuador (2013-2017).PLoS neglected tropical diseases · 2020Article
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Authors and funding
3 authors.
Funding
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Abstract
objectivesThis study examines the impact of the type of method used on the estimation of the burden of diseases.
designComparison of methods of estimating disease burden.
settingFour metrics of burden of disease estimation, namely, years of potential life lost (YPLL), non-age weighted years of life lost (YLL) without discounting and YLL with uniform or non-uniform age weighting and discounting were used to calculate the burden of selected diseases in three countries: Australia, USA and South Africa.
participantsMortality data for all individuals from birth were obtained from the WHO database. OUTCOMES: The burden of 10 common diseases with four metrices, and the relative contribution of each disease to the overall national burden when each metric is used.
resultsThere were variations in the burden of disease estimates with the four methods. The standardised YPLL estimates were higher than other methods of calculation for diseases common among young adults and lower for diseases common among the elderly. In the three countries, discounting decreased the contributions of diseases common among younger adults to the total burden of disease, while the contributions of diseases of the elderly increased. After discounting with age weighting, there were no distinct patterns for diseases of the elderly and young adults in the three countries.
conclusionsGiven the variability in the estimates of the burden of disease with different approaches, there should be transparency regarding the type of metric used and a generally acceptable method that incorporates all the relevant social values should be developed.
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