Evidence map›Paper›PMID 31427304›Full record

ArticleAntimicrobial agents and chemotherapy2019

Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis.

Nathan P Wiederhold, Laura K Najvar, Karen J Shaw, Rosie Jaramillo, Hoja Patterson, Marcos Olivo, Gabriel Catano, Thomas F Patterson

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Review
  3. New Perspectives on Antimicrobial Agents: Fosmanogepix.Antimicrobial agents and chemotherapy · 2026
    Review
  4. Manogepix demonstrates potentAntimicrobial agents and chemotherapy · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Fungal lung disease.The European respiratory journal · 2024
    Review
  11. A Mini-Review of In Vitro Data forJournal of fungi (Basel, Switzerland) · 2024
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Recent Antifungal Pipeline Developments againstJournal of fungi (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nathan P WiederholdUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA wiederholdn@uthscsa.edu.ORCID 0000-0002-2225-5122
Laura K NajvarUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Karen J ShawAmplyx Pharmaceuticals, Inc., San Diego, California, USA.
Rosie JaramilloUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Hoja PattersonUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Marcos OlivoUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Gabriel CatanoUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Thomas F PattersonUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
The University of Texas Health Science Center at San Antonio · USAmplyx Pharmaceuticals (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emerging pathogenic yeast

Indexed as

AnimalsAntifungal AgentsCandidaCandidiasis, InvasiveCaspofunginDisease Models, AnimalDrug Resistance, FungalFluconazoleMiceMicrobial Sensitivity TestsAntifungal AgentsCaspofunginFluconazoleAPX001APX001ACandida aurisexperimental candidiasisfluconazole resistancefosmanogepixglycosylphosphatidylinositol anchor biosynthesis pathwayGwt1invasive candidiasismanogepixmurine model

Identifiers

PMID31427304
PMCPMC6811405
OpenAlexW2969037002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.