Evidence map›Paper›PMID 31427296›Full record

ArticleAntimicrobial agents and chemotherapy2019

Influence of Sustained Low-Efficiency Dialysis Treatment on Isavuconazole Plasma Levels in Critically Ill Patients.

Tobias Lahmer, Gonzalo Batres Baires, Markus Heilmaier, Roland M Schmid, Fritz Sörgel, Martina Kinzig, Wolfgang Huber, Ulrich Mayr, Sebastian Rasch

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Reply to Baud and Houzé, "ShouldAntimicrobial agents and chemotherapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tobias LahmerKlinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany tobiaslahmer@me.com.
Gonzalo Batres BairesKlinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany.
Markus HeilmaierKlinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany.
Roland M SchmidKlinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany.
Fritz SörgelInstitute for Biomedical and Pharmaceutical Research (IBMP), Nürnberg-Heroldsberg, Germany.
Martina KinzigInstitute for Biomedical and Pharmaceutical Research (IBMP), Nürnberg-Heroldsberg, Germany.
Wolfgang HuberKlinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany.
Ulrich MayrKlinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany.
Sebastian RaschKlinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der Technischen Universität Munich, Munich, Germany.
Klinikum rechts der Isar · DEInstitute for Biomedical and Pharmaceutical Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isavuconazole plasma concentrations were measured before and after sustained low-efficiency dialysis (SLED) treatment in 22 critically ill adult patients with probable invasive aspergillosis and underlying hematological malignancies. Isavuconazole levels were significantly lower after SLED treatment (5.73 versus 3.36 μg/ml;

Indexed as

AdultAntifungal AgentsAspergillosisAspergillusCritical IllnessFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedNitrilesPyridinesTriazolesAntifungal AgentsisavuconazoleNitrilesPyridinesTriazolescritically illinvasive aspergillosisisavuconazoleSLEDtherapeutic drug monitoring

Identifiers

PMID31427296
PMCPMC6811396
OpenAlexW2968348060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.