Evidence map›Paper›PMID 31427286›Full record

ReviewCold Spring Harbor perspectives in medicine2019

PTEN in the Stroma.

Katie A Thies, Julia E Lefler, Gustavo Leone, Michael C Ostrowski

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Katie A ThiesDepartment of Radiation Oncology and The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.
Julia E LeflerDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina 29425, USA.
Gustavo LeoneDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina 29425, USA.
Michael C OstrowskiDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina 29425, USA.
MUSC Hollings Cancer Center · USMedical University of South Carolina · USThe Ohio State University · US

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RAYMOND N. DUBOIS · 2009 to 2026
$42.7M
Suppression of Mammary Tumorigenesis by Stromal p53P01CA097189 · NCI · OHIO STATE UNIVERSITY · PI FERNANDEZ, SOLEDAD A · 2004 to 2016
$16.1M
NCI NIH HHS P01 CA097189NCI NIH HHS P30 CA138313
6 · The paper itself

Abstract

Although tremendous progress has been made in understanding the functions of

Indexed as

Gene Expression Regulation, NeoplasticHumansPTEN PhosphohydrolaseSignal TransductionStromal CellsTumor MicroenvironmentPTEN PhosphohydrolasePTEN protein, human

Identifiers

PMID31427286
PMCPMC6771362
OpenAlexW2969952318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.