Evidence map›Paper›PMID 31426864›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2019

Ziren Kong, Yusong Lin, Chendan Jiang, Longfei Li, Zehua Liu, Yuekun Wang, Congxin Dai, Delin Liu, Xuying Qin, Yu Wang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
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  7. Article
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  11. Article
  12. PrognosticDiagnostics (Basel, Switzerland) · 2023
    Article
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  15. Article
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  18. Article
  19. Article
  20. Brain Tumor Imaging: Applications of Artificial Intelligence.Seminars in ultrasound, CT, and MR · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Ziren KongDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.
Yusong LinCollaborative Innovation Center for Internet Healthcare, Zhengzhou University, No.75 Daxue Road, Erqi District, Zhengzhou, Henan, China.
Chendan JiangDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.
Longfei LiCollaborative Innovation Center for Internet Healthcare, Zhengzhou University, No.75 Daxue Road, Erqi District, Zhengzhou, Henan, China.
Zehua LiuCollaborative Innovation Center for Internet Healthcare, Zhengzhou University, No.75 Daxue Road, Erqi District, Zhengzhou, Henan, China.
Yuekun WangDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.
Congxin DaiDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.
Delin LiuDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.
Xuying QinDepartment of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.
Yu WangDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China.
Zhenyu LiuKey Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Science, No.80 East Zhongguancun Road, Haidian District, Beijing, China.
Xin ChengDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China. pumch_chengxin@126.com.ORCID http://orcid.org/0000-0002-7836-8724
Jie TianKey Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Science, No.80 East Zhongguancun Road, Haidian District, Beijing, China. jie.tian@ia.ac.cn.
Wenbin MaDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, China. mawb2001@hotmail.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNZhengzhou University · CNTianjin University of Science and Technology · CNXidian University · CN

Funding

Beijing Natural Science Foundation 7182109Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences 2016-I2M-2-001Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences 2018-I2M-3-001Chinese Academy of Sciences GJJSTD20170004Chinese Academy of Sciences QYZDJ-SSW-JSC005Fundamental Research Funds for the Central Universities 3332018029National Natural Science Foundation of China 81772009National Natural Science Foundation of China 81772012Scientific and Technological Research Project of Henan Province 182102310162Youth Innovation Promotion Association of Chinese Academy of Sciences 2019136
6 · The paper itself

Abstract

backgroundThe methylation status of the O

methodsOne hundred and seven pathology-confirmed primary diffuse glioma patients were retrospectively included and randomly assigned to the primary (n = 71) or validation cohort (n = 36). The MGMT promoter methylation status was measured by pyrosequencing. A total of 1561 radiomics features were extracted from the three-dimensional region of interest (ROI) on the standard uptake value (SUV) maps that were generated from the original

resultsFive radiomics features were selected to construct the radiomics signature, and displayed the best performance with area under the receiver operating characteristic (ROC) curve (AUC) reaching 0.94 and 0.86 in the primary and validation cohorts, respectively, which outweigh the performances of clinical signature and fusion signature. With a median follow-up time of 32.4 months, the radiomics signature stratified the glioma patients into two risk groups with significantly different prognoses (p = 0.04).

conclusions

Indexed as

DNA MethylationPositron-Emission TomographyAdultAgedBrain NeoplasmsDNA Modification MethylasesDNA Repair EnzymesFemaleFluorodeoxyglucose F18GliomaHumansMaleMiddle AgedPromoter Regions, GeneticRadiopharmaceuticalsTumor Suppressor ProteinsDNA Modification MethylasesDNA Repair EnzymesFluorodeoxyglucose F18MGMT protein, humanRadiopharmaceuticalsTumor Suppressor ProteinsFDG PETGliomaMGMT promoter methylationPrognosisRadiomics

Identifiers

PMID31426864
PMCPMC6701097
OpenAlexW2969320815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.