ArticleGenetics, selection, evolution : GSE2019
A bivariate genomic model with additive, dominance and inbreeding depression effects for sire line and three-way crossbred pigs.
Article in Genetics, selection, evolution : GSE, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 66 citations in OpenAlex.
- Expression genome-wide association study identifies key regulatory variants enriched with metabolic and immune functions in four porcine tissues.BMC genomics · 2024Article
- Genetic parameters for pelvic organ prolapse in purebred and crossbred sows.Frontiers in genetics · 2024Article
- Selection for social genetic effects in purebred pigs improves behaviour and handling of their crossbred progeny.Genetics, selection, evolution : GSE · 2023Article
- Genomic prediction in pigs using data from a commercial crossbred population: insights from the Duroc x (Landrace x Yorkshire) three-way crossbreeding system.Genetics, selection, evolution : GSE · 2023Article
- Impacts of additive, dominance, and inbreeding depression effects on genomic evaluation by combining two SNP chips in Canadian Yorkshire pigs bred in China.Genetics, selection, evolution : GSE · 2022Article
- Genomic Prediction Methods Accounting for Nonadditive Genetic Effects.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Genome-wide scan for runs of homozygosity identifies candidate genes in Wannan Black pigs.Animal bioscience · 2021Article
- Purebred-crossbred genetic parameters for reproductive traits in swine.Journal of animal science · 2021Article
- Review: optimizing genomic selection for crossbred performance by model improvement and data collection.Journal of animal science · 2021Review
- Selective genotyping and phenotypic data inclusion strategies of crossbred progeny for combined crossbred and purebred selection in swine breeding.Journal of animal science · 2021Article
- Editorial: Advances in Genomics of Crossbred Farm Animals.Frontiers in genetics · 2021Article
- Heterosis and Hybrid Crop Breeding: A Multidisciplinary Review.Frontiers in genetics · 2021Review
- Impact of inclusion rates of crossbred phenotypes and genotypes in nucleus selection programs.Journal of animal science · 2020Article
- Optimizing genomic reference populations to improve crossbred performance.Genetics, selection, evolution : GSE · 2020Article
- Correction to: A bivariate genomic model with additive, dominance and inbreeding depression effects for sire line and three-way crossbred pigs.Genetics, selection, evolution : GSE · 2020Article
- Development of a low-density panel for genomic selection of pigs in Russia.Translational animal science · 2020Article
- A Review of Genomic Models for the Analysis of Livestock Crossbred Data.Frontiers in genetics · 2020Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundCrossbreeding is widely used in pig production because of the benefits of heterosis effects and breed complementarity. Commonly, sire lines are bred for traits such as feed efficiency, growth and meat content, whereas maternal lines are also bred for reproduction and longevity traits, and the resulting three-way crossbred pigs are used for production of meat. The most important genetic basis for heterosis is dominance effects, e.g. removal of inbreeding depression. The aims of this study were to (1) present a modification of a previously developed model with additive, dominance and inbreeding depression genetic effects for analysis of data from a purebred sire line and three-way crossbred pigs; (2) based on this model, present equations for additive genetic variances, additive genetic covariance, and estimated breeding values (EBV) with associated accuracies for purebred and crossbred performances; (3) use the model to analyse four production traits, i.e. ultra-sound recorded backfat thickness (BF), conformation score (CONF), average daily gain (ADG), and feed conversion ratio (FCR), recorded on Danbred Duroc and Danbred Duroc-Landrace-Yorkshire crossbred pigs reared in the same environment; and (4) obtain estimates of genetic parameters, additive genetic correlations between purebred and crossbred performances, and EBV with associated accuracies for purebred and crossbred performances for this data set.
resultsAdditive genetic correlations (with associated standard errors) between purebred and crossbred performances were equal to 0.96 (0.07), 0.83 (0.16), 0.75 (0.17), and 0.87 (0.18) for BF, CONF, ADG, and FCR, respectively. For BF, ADG, and FCR, the additive genetic variance was smaller for purebred performance than for crossbred performance, but for CONF the reverse was observed. EBV on Duroc boars were more accurate for purebred performance than for crossbred performance for BF, CONF and FCR, but not for ADG.
conclusionsMethodological developments led to equations for genetic (co)variances and EBV with associated accuracies for purebred and crossbred performances in a three-way crossbreeding system. As illustrated by the data analysis, these equations may be useful for implementation of genomic selection in this system.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.