ArticleTechnology in cancer research & treatment2019
A Collimator Setting Optimization Algorithm for Dual-Arc Volumetric Modulated Arc Therapy in Pancreas Stereotactic Body Radiation Therapy.
Article in Technology in cancer research & treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Dosimetric advantages of dual arc increments for head and neck volumetric-modulated arc therapy in the Monaco treatment planning system.Journal of applied clinical medical physics · 2025Article
- Dosimetric analysis of orthogonal collimator configuration in volumetric modulated arc therapy planning: a comparative study.Frontiers in oncology · 2025Article
- Incorporating Case-Based Reasoning for Radiation Therapy Knowledge Modeling: A Pelvic Case Study.Technology in cancer research & treatment · 2019Article
- Radiotherapy Treatment Planning in the Age of AI: Are We Ready Yet?Technology in cancer research & treatmentArticle
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Authors and funding
7 authors.
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Abstract
purposeTo optimize collimator setting to improve dosimetric quality of pancreas volumetric modulated arc therapy plan for stereotactic body radiation therapy. MATERIALS AND
methodsFifty-five volumetric modulated arc therapy cases in stereotactic body radiation therapy of pancreas were retrospectively included in this study with internal review board approval. Different from the routine practice of initializing collimator settings with a template, the proposed algorithm simultaneously optimizes the collimator angles and jaw positions that are customized to the patient geometry. Specifically, this algorithm includes 2 key steps: (1) an iterative optimization algorithm via simulated annealing that generates a set of potential collimator settings from 39 cases with pancreas stereotactic body radiation therapy, and (2) a multi-leaf collimator modulation scoring system that makes the final decision of the optimal collimator settings (collimator angles and jaw positions) based on organs at risk sparing criteria. For validation, the other 16 cases with pancreas stereotactic body radiation therapy were analyzed. Two plans were generated for each validation case, with one plan optimized using the proposed algorithm (
resultsBoth plan groups had comparable target dose coverage and mean doses of all organs at risk. However, organs at risk (stomach, duodenum, large/small bowel) maximum dose sparing (
conclusionsThe proposed collimator settings optimization algorithm successfully improved dosimetric performance for dual-arc pancreas volumetric modulated arc therapy plans in stereotactic body radiation therapy of pancreas. This algorithm has the capability of immediate clinical application.
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