Evidence map›Paper›PMID 31426616›Full record

ReviewMedicina (Kaunas, Lithuania)2019

Component-Resolved Diagnosis in Food Allergies.

Elisabetta Calamelli, Lucia Liotti, Isadora Beghetti, Valentina Piccinno, Laura Serra, Paolo Bottau

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Clinical Proteomics Applied to Food Allergy.Advances in experimental medicine and biology · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Immunoglobulin E (IgE)-mediated food allergy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Review
  14. Review
  15. Identifying patients at risk of anaphylaxis.The World Allergy Organization journal · 2024
    Review
  16. Article
  17. The future of food allergy diagnosis.Frontiers in allergy · 2024
    Review
  18. Review
  19. Modern Concept of Molecular Diagnostics of Allergy to Dogs.Bulletin of experimental biology and medicine · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elisabetta CalamelliPediatric and Neonatology Unit, Imola Hospital, 40026 Imola, Italy. e.calamelli@ausl.imola.bo.it.
Lucia LiottiPediatric Unit, Civic Hospital, 60019 Senigallia, Italy.
Isadora BeghettiPediatric Unit, Department of Medical and Surgical Sciences (DIMEC), S.Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-4819-1830
Valentina PiccinnoPediatric and Neonatology Unit, Imola Hospital, 40026 Imola, Italy.
Laura SerraPediatric and Neonatology Unit, Imola Hospital, 40026 Imola, Italy.
Paolo BottauPediatric and Neonatology Unit, Imola Hospital, 40026 Imola, Italy.
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Component-resolved diagnostics (CRD) in food allergies is an approach utilized to characterize the molecular components of each allergen involved in a specific IgE (sIgE)-mediated response. In the clinical practice, CRD can improve diagnostic accuracy and assist the physician in many aspects of the allergy work-up. CRD allows for discriminatory co-sensitization versus cross-sensitization phenomena and can be useful to stratify the clinical risk associated with a specific sensitization pattern, in addition to the oral food challenge (OFC). Despite this, there are still some unmet needs, such as the risk of over-prescribing unnecessary elimination diets and adrenaline auto-injectors. Moreover, up until now, none of the identified sIgE cutoff have shown a specificity and sensitivity profile as accurate as the OFC, which is the gold standard in diagnosing food allergies. In light of this, the aim of this review is to summarize the most relevant concepts in the field of CRD in food allergy and to provide a practical approach useful in clinical practice.

Indexed as

AllergensFood HypersensitivityHumansImmunoglobulin ESensitivity and SpecificitySkin TestsAllergensImmunoglobulin Ealfa-galcaseingliadinlipid transfer proteinovomucoidparvalbumintropomyosin

Identifiers

PMID31426616
PMCPMC6723663
OpenAlexW2969162539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.