ArticleMolecules (Basel, Switzerland)2019
Optimization of Ultrasonic-Assisted Extraction and Purification of Zeaxanthin and Lutein in Corn Gluten Meal.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 37 citations in OpenAlex.
- Article
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- Screening of novel β-carotene hydroxylases for the production of β-cryptoxanthin and zeaxanthin and the impact of enzyme localization and crowding on their production in Yarrowia lipolytica.Microbial cell factories · 2024Article
- Optimization of accelerated solvent extraction of zeaxanthin from orange paprika using response surface methodology and an artificial neural network coupled with a genetic algorithm.Food science and biotechnology · 2024Article
- Comprehensive Analysis of Lutein and Loroxanthin inMolecules (Basel, Switzerland) · 2024Article
- Development and Utilization of Corn Processing by-Products: A Review.Foods (Basel, Switzerland) · 2022Review
- Ultrasound-Assisted Extraction of Flavonoids fromMolecules (Basel, Switzerland) · 2022Article
- Impact of low-frequency ultrasound technology on physical, chemical and technological properties of cereals and pseudocereals.Ultrasonics sonochemistry · 2022Review
- Isolation, identification, and characterization of corn-derived antioxidant peptides from corn fermented milk byFrontiers in nutrition · 2022Article
- Optimization of Taxol Extraction Process Using Response Surface Methodology and Investigation of Temporal and Spatial Distribution of Taxol inMolecules (Basel, Switzerland) · 2021Article
- Optimization of Lutein Recovery fromBiomolecules · 2021Article
- Microwave-Assisted Improved Extraction and Purification of Anticancer Nimbolide fromMolecules (Basel, Switzerland) · 2020Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Zeaxanthin and lutein have a wide range of pharmacological applications. In this study, we conducted systematic experimental research to optimize antioxidant extraction based on detection, extraction, process amplification, and purification. An ultrasonic-assisted method was used to extract zeaxanthin and lutein with high efficiency from corn gluten meal. Firstly, the effects of solid-liquid ratio, extraction temperature, and ultrasonic extraction time on the extraction of zeaxanthin were investigated in single-factor experiments. The optimization extraction parameters of zeaxanthin and lutein with ethanol solvent were obtained using the response surface methodology (RSM) as follows: liquid-solid ratio of 7.9:1, extraction temperature of 56 °C, and extraction time of 45 min. The total content of zeaxanthin and lutein was 0.501%. The optimum extraction experimental parameters were verified by process amplification, and we confirmed that the parameters of the extraction process optimized using the RSM design are reliable and precise. Zeaxanthin and lutein from crude extract of corn gluten were separated and purified using silica gel column chromatography with the purity of zeaxanthin increasing from 0.28% to 31.5% (about 110 times) and lutein from 0.25% to 16.3% (about 65 times), which could be used for large-scale industrial production of carotenoids.
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