Evidence map›Paper›PMID 31426519›Full record

ArticleJournal of clinical medicine2019

Left Atrial Strain to Identify Diastolic Dysfunction in Children with Cardiomyopathies.

Jolanda Sabatino, Giovanni Di Salvo, Costantina Prota, Valentina Bucciarelli, Manjit Josen, Josefa Paredes, Nunzia Borrelli, Domenico Sirico, Sanjay Prasad, Ciro Indolfi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Left Atrial Strain in Pediatric Cardiology: Evidence to Date and Future Directions.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026
    Review
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  11. Review
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  13. How to behave with paediatric myocarditis: imaging methods and clinical considerations.European heart journal. Imaging methods and practice · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Jolanda SabatinoDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.ORCID 0000-0002-1661-5419
Giovanni Di SalvoDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK. G.DiSalvo@rbht.nhs.uk.
Costantina ProtaDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Valentina BucciarelliDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Manjit JosenDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Josefa ParedesDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Nunzia BorrelliDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Domenico SiricoDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Sanjay PrasadDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Ciro IndolfiDivision of Cardiology, Department of Medical and Surgical Science, URT-CNR, Magna Graecia University, 88100 Catanzaro, Italy.
Alain FraisseDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Piers E F DaubeneyDepartment of Paediatric Cardiology, Royal Brompton Hospital, London SW36NP, UK.
Royal Brompton Hospital · GBMagna Graecia University · IT

Funding

European Society of Cardiology ESC Training Grant 2019
6 · The paper itself

Abstract

backgroundLeft ventricular (LV) diastolic dysfunction (DD) carries worse prognosis in childhood. 2-dimensional (2-D) left atrial (LA) strain accurately categorizes DD in adults but its role in children is unknown. Thus, the aim of this study is to investigate whether LA strain and strain rate could diagnose and classify DD in children with dilated (CMD), hypertrophic (HCM) and restrictive (RCM) cardiomyopathies (CM). METHODS AND

resultsThe study includes 136 children (aged 8.8 ± 6 years): 44 with DCM, 40 with HCM, 7 with RCM and 45 healthy controls (CTRL). They underwent standard echocardiographic examination and 2-D speckle-tracking analyses (LV longitudinal peak systolic strain (LS), LA peak systolic strain and strain rate). No significant differences in mitral E/A and pulmonary S/D ratios were observed among the four groups. Although E/E' and indexed left atrial volumes were found to be significantly higher in HCM, DCM and RCM compared to CTRL (

conclusionsLA strain and strain rate could be a promising tool to better understand and classify DD in children with cardiomyopathies, opening the way to its clinical use.

Indexed as

atrial straincardiomyopathychildrendiastolic function

Identifiers

PMID31426519
PMCPMC6722665
OpenAlexW2967068505

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.