Evidence map›Paper›PMID 31426502›Full record

ArticleMicroorganisms2019

Administration of a Postbiotic Causes Immunomodulatory Responses in Broiler Gut and Reduces Disease Pathogenesis Following Challenge.

Casey N Johnson, Michael H Kogut, Kenneth Genovese, Haiqi He, Steve Kazemi, Ryan J Arsenault

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Review
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  9. Application ofIranian journal of microbiology · 2025
    Review
  10. Article
  11. Postbiotics: an insightful review of the latest category in functional biotics.World journal of microbiology & biotechnology · 2025
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Efficacy ofAnimals : an open access journal from MDPI · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Casey N JohnsonDepartment of Animal and Food Sciences, University of Delaware, Newark, DE 19716, USA.
Michael H KogutSouthern Plains Agricultural Research Center, USDA ARS, College Station, TX 77845, USA.
Kenneth GenoveseSouthern Plains Agricultural Research Center, USDA ARS, College Station, TX 77845, USA.
Haiqi HeSouthern Plains Agricultural Research Center, USDA ARS, College Station, TX 77845, USA.
Steve KazemiPure Cultures Inc., Denver, CO 80216, USA.
Ryan J ArsenaultDepartment of Animal and Food Sciences, University of Delaware, Newark, DE 19716, USA. rja@udel.edu.
Southern Plains Agricultural Research Center · USUniversity of Delaware · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the reemergence of poultry diseases such as necrotic enteritis following the restriction of in-feed antibiotics, the search for antibiotic alternatives has become critically important. Postbiotics are non-viable bacterial products or metabolic byproducts from probiotic microorganisms that have positive effects on the host or microbiota. These are a promising alternative to antibiotics. Here, we describe the mechanism of action of a postbiotic in the context of a

Indexed as

chickenClostridium perfringensgutimmunomodulatorykinomepostbiotic

Identifiers

PMID31426502
PMCPMC6723925
OpenAlexW2968180219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.