Evidence map›Paper›PMID 31426471›Full record

ArticleMarine drugs2019

New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca

Stefano D'Errico, Emy Basso, Andrea Patrizia Falanga, Maria Marzano, Tullio Pozzan, Vincenzo Piccialli, Gennaro Piccialli, Giorgia Oliviero, Nicola Borbone

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stefano D'ErricoDipartimento di Farmacia, Università degli Studi di Napoli Federico II, via Domenico Montesano 49, Napoli 80131, Italy.
Emy BassoConsiglio Nazionale delle Ricerche, Dipartimento di Scienze Biomediche, Istituto di Neuroscienze (Sezione di Padova), viale Giuseppe Colombo 3, Padova 35131, Italy.
Andrea Patrizia FalangaDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, via Sergio Pansini 5, Napoli 80131, Italy.
Maria MarzanoDipartimento di Farmacia, Università degli Studi di Napoli Federico II, via Domenico Montesano 49, Napoli 80131, Italy.
Tullio PozzanConsiglio Nazionale delle Ricerche, Dipartimento di Scienze Biomediche, Istituto di Neuroscienze (Sezione di Padova), viale Giuseppe Colombo 3, Padova 35131, Italy.
Vincenzo PiccialliDipartimento di Scienze Chimiche, Università degli Studi di Napoli Federico II, via Cintia, 26, Napoli 80126, Italy.ORCID 0000-0003-4628-7548
Gennaro PiccialliDipartimento di Farmacia, Università degli Studi di Napoli Federico II, via Domenico Montesano 49, Napoli 80131, Italy.
Giorgia OlivieroDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, via Sergio Pansini 5, Napoli 80131, Italy. golivier@unina.it.ORCID 0000-0003-0765-2127
Nicola BorboneDipartimento di Farmacia, Università degli Studi di Napoli Federico II, via Domenico Montesano 49, Napoli 80131, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report on the synthesis of a small set of linear precursors of an inosine analogue of cyclic ADP-ribose (cADPR), a second messenger involved in Ca

Indexed as

AnimalsCalciumCalcium SignalingCell DifferentiationCyclic ADP-RiboseEggsRyanodine Receptor Calcium Release ChannelSea UrchinsSecond Messenger SystemsStructure-Activity RelationshipCalciumCyclic ADP-RiboseRyanodine Receptor Calcium Release ChannelC2C12 cellscADPRcaffeinecalcium mobilizationIP3neuroblastomaphosphorylationryanodine receptors

Identifiers

PMID31426471
PMCPMC6723567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.