ReviewInternational journal of molecular sciences2019
The Role of Nrf2 in the Antioxidant Cellular Response to Medical Ozone Exposure.
3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 82 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
11.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
NCT06706544 phase2 / phase3recruitingnot on this mapstarted 2025, after this paper: background citation
Effectiveness and Cost-effectiveness of Ozone Treatment in Patients With Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy. Randomized, Triple-blind Clinical Trial (OzoParQT)
NCT06799351 phase2 / phase3recruitingnot on this mapstarted 2025, after this paper: background citation
Evaluation of the Gut Microbiome Profiles in Patients with Chemotherapy-induced Peripheral Neuropathy Treated in the Randomized Clinical Trial with Ozone OzoParQT (NCT06706544).
Gene and Molecular Pathway Characterization of the Response to Ozone Treatment in Gynecological Tumor Patients With Chronic Pelvic Pain Secondary to Radio-chemotherapy
Who cites it
82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- Effectiveness and Safety of Ozone Therapy in Humans: An Umbrella Review of Systematic Reviews with Meta-Analyses of Randomized Clinical Trials.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Mitochondrial Dysfunction, Its Oxidative Stress-Induced Pathologies and Redox Bioregulation through Low-Dose Medical Ozone: A Systematic Review.Molecules (Basel, Switzerland) · 2024Pooled it
- A pilot study for treatment of COVID-19 patients in moderate stage using intravenous administration of ozonized saline as an adjuvant treatment-registered clinical trial.International immunopharmacology · 2021Trial
- Efficacy of ozonized water for the treatment of erosive oral lichen planus: a randomized controlled study.Medicina oral, patologia oral y cirugia bucal · 2020Trial
- Harnessing gasotransmitters for orthopaedic infection therapy: Mechanisms and advanced delivery platforms.Bioactive materials · 2027Review
- Comparison of HDL-Associated Antioxidant Activities and Anti-Inflammatory Effect Between Ozonated Sunflower Oil (OSO) and Ozonated Olive Oil (OOO) Under Carboxymethyllysine-Induced Acute Phase in Zebrafish Adults and Embryos.Antioxidants (Basel, Switzerland) · 2026Article
- The cell with many faces: lung macrophage plasticity and function in response to environmental and pathogenic insults.Physiological reviews · 2026Review
- Comparison of ozone administration routes on liver, lung, and brain damage after spinal cord ischemia-reperfusion injury.World journal of experimental medicine · 2026Article
- Chronic ambient air pollution and the incidence of blepharitis and blepharoconjunctivitis: a nationwide population-based cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Olfactory and Cognitive Performance Improvement After Oxygen-Ozone Major Autohemotherapy in Mild Cognitive Impairment: A Retrospective Cohort Study.Neurology international · 2026Article
- Depressive symptoms mediate the associations between air pollution exposure and anemia risk: a nationwide longitudinal study in China.BMC public health · 2026Article
- Mild Ozone-Induced Oxidative Stress Modulates the Activity and Viability of Porcine Neutrophils and Monocytes.Animals : an open access journal from MDPI · 2026Article
- Ozone Micro-Nano Bubbles Application Controls Disease Development and Maintains Quality of FreshJournal of fungi (Basel, Switzerland) · 2026Article
- Association between air pollution and incident cardiovascular diseases among a population with cardiovascular-kidney-metabolic syndrome stages 0-3: the first evidence from the China Health and Retirement Longitudinal Study.Frontiers in endocrinology · 2026Article
- Response by Chirumbolo to "Rare Localized Adverse Reaction to Botulinum Toxin Type A in a Patient Without Allergic History: A Case Report" by Muner et al.Aesthetic surgery journal. Open forum · 2026Article
- The association between air pollutants and mild cognitive impairment in Taiwanese elderly.International journal of medical sciences · 2026Article
- Ozone protects against ischemia-reperfusion injury: molecular mechanisms.Frontiers in pharmacology · 2026Review
- Modulating the Gut Microbiota via Rectal Ozone Insufflation in Gynecological Cancer Patients with Radiotherapy/Chemotherapy-Induced Pelvic Toxicity: A Proposed Clinical Study Protocol.Journal of clinical medicine · 2025Article
- Medical Ozone Treatment Attenuates Male Reproductive Toxicity Induced by Bleomycin, Etoposide, and Cisplatin Regimen in an Experimental Animal Model.International journal of molecular sciences · 2025Article
- Ozone water enema activates SIRT1-Nrf2/HO-1 pathway to ameliorate gut dysbiosis in mice receiving COVID-19 patient-derived faecal microbiota.Journal of medical microbiology · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Mirco GalièDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie 8, I-37134 Verona, Italy.
Viviana CoviSan Rocco Clinic, Via Monsignor G. V. Moreni 95, I-25018 Montichiari (BS), Italy.
Gabriele TabaracciSan Rocco Clinic, Via Monsignor G. V. Moreni 95, I-25018 Montichiari (BS), Italy.
Manuela MalatestaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Strada Le Grazie 8, I-37134 Verona, Italy. manuela.malatesta@univr.it.ORCID 0000-0001-8196-9232
University of Verona · IT
Funding
Università degli Studi di Verona Joint Project 2017
Abstract
Ozone (O
Indexed as
InflammationOxidative StressAnimalsAntioxidantsHumansNeoplasmsNF-E2-Related Factor 2OzoneTreatment OutcomeAntioxidantsNF-E2-Related Factor 2Ozoneadipose biologycancerinflammationmitochondriaoxidative stressozone therapyproteostasis
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.