ArticleJournal of clinical medicine2019
Open access · goldAbstract read
In one paragraph
Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- A reappraisal of APOE genetic effects on Alzheimer's disease risk in the Japanese population: a meta-analysis.Molecular neurodegeneration · 2026Pooled it
- The effect of curcumin supplementation on cognitive function: an updated systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- A multiancestry polygenic risk score for Alzheimer's disease is associated with cognitive decline and neuropathological hallmarks in diverse populations.Nature genetics · 2026Article
- The Association BetweenNeurology. Genetics · 2026Article
- Article
- A clinically feasible framework to estimate tau pathology and clinical-biological discordance in the Alzheimer's disease spectrum.Alzheimer's research & therapy · 2026Article
- A common 19 bp APOE enhancer deletion is protective against Alzheimer's disease in African Americans.Nature communications · 2026Article
- Association between apolipoprotein E gene polymorphisms and the effects of high-intensity interval training on body composition in university students.Frontiers in nutrition · 2026Article
- The Gwangju Alzheimer's & Related Dementias (GARD) cohort: Over a decade of Asia's largest longitudinal multimodal study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- APOE4 to APOE2 allelic switching in mice improves Alzheimer's disease-related metabolic signatures, neuropathology and cognition.Nature neuroscience · 2025Article
- A Japanese registry for optimizing the safe use of anti-amyloid therapies for Alzheimer's disease in Japan.Nature aging · 2025Article
- A multi-ancestry polygenic risk score for Alzheimer disease is associated with cognitive decline, hippocampal atrophy and neuropathological hallmarks in diverse populations.medRxiv : the preprint server for health sciences · 2025Article
- Bioinformatic and genomic analysis identifies C allele of APOE rs7412 as the most prominent variant limiting extreme human longevity.Scientific reports · 2025Article
- Neur-Ally: a deep learning model for regulatory variant prediction based on genomic and epigenomic features in brain and its validation in certain neurological disorders.NAR genomics and bioinformatics · 2025Article
- Apolipoprotein E in Alzheimer's disease: molecular insights and therapeutic opportunities.Molecular neurodegeneration · 2025Review
- Association of rs440446 in the APOE intron region with multidimensional cognitive function, lipid/metabolic markers, and spontaneous neural activity in Chinese urban community-dwelling older adults.Frontiers in neuroscience · 2025Article
- Whole-genome sequencing study in Koreans identifies novel loci for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Apolipoprotein E and Alzheimer's Disease in Italian Population: Systematic Review and Meta-Analysis.Brain sciences · 2024Review
- Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
55 authors at 20 institutions in 4 countries.
Kyu Yeong ChoiNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Jang Jae LeeNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Tamil Iniyan GunasekaranNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.ORCID 0000-0002-8639-5060
Sarang KangNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Wooje LeeNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Jangho JeongDepartment of Life Science, Chung-Ang University, Seoul 06974, Korea.
Ho Jae LimNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.ORCID 0000-0003-0115-5170
Xiaoling ZhangDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118, USA.
Congcong ZhuDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118, USA.ORCID 0000-0002-1657-8726
So-Yoon WonDepartment of Biochemistry and Signaling Disorder Research Center, College of Medicine, Chungbuk National University, Cheongju 28644, Korea.
Yu Yong ChoiNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Eun Hyun SeoNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Seok Cheol LeeNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Jungsoo GimNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Ji Yeon ChungNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Ari ChongNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Min Soo ByunDepartment of Neuropsychiatry, Seoul National University Hospital, Seoul 03080, Korea.
Sujin SeoDepartment of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul 08826, Korea.
Pan-Woo KoDepartment of Neurology, Kyungpook National University School of Medicine, Daegu 41944, Korea.
Ji-Won HanDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do 13620, Korea.
Catriona McLeanDepartment of Pathology, The Alfred Hospital, Melbourne, Victoria 3004, Australia.
John FarrellDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118, USA.
Kathryn L LunettaDepartment of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
Akinori MiyashitaDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata 951-8585, Japan.ORCID 0000-0003-2508-9649
Norikazu HaraDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata 951-8585, Japan.
Sungho WonDepartment of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-5751-5089
Seong-Min ChoiDepartment of Neurology, Chonnam National University Medical School, Gwangju 61469, Korea.
Jung-Min HaNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Jee Hyang JeongDepartment of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul 07985, Korea.
Ryozo KuwanoDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata 951-8585, Japan.
Min Kyung SongChonnam national university Gwangju 2nd geriatric hospital, Gwangju 61748, Korea.
Seong Soo A AnDepartment of Bionanotechnology, Gachon University, Seongnam, Gyeonggi-do 13120, Korea.
Young Min LeeDepartment of Psychiatry, Pusan National University School of Medicine, Busan 50612, Korea.
Kyung Won ParkDepartment of Neurology, Donga University College of Medicine, Busan 49315, Korea.ORCID 0000-0002-6788-5267
Ho-Won LeeDepartment of Neurology, Kyungpook National University School of Medicine, Daegu 41944, Korea.ORCID 0000-0002-8849-920X
Seong Hye ChoiDepartment of Neurology, Inha University School of Medicine, Incheon 22212, Korea.
Sangmyung RheeDepartment of Life Science, Chung-Ang University, Seoul 06974, Korea.
Woo Keun SongBio Imaging and Cell Logistics Research Center, School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.
Jung Sup LeeNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.
Richard MayeuxDepartment of Neurology and Sergievsky Center, Columbia University, New York, NY 10032, USA.
Jonathan L HainesDepartment of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH 44106, USA.
Margaret A Pericak-VanceHussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL 33101, USA.
I L Han ChooDepartment of Neuropsychiatry, Chosun University School of Medicine and Hospital, Gwangju 61453, Korea.
Kwangsik NhoDepartment of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Ki-Woong KimDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do 13620, Korea.
Dong Young LeeDepartment of Neuropsychiatry, Seoul National University Hospital, Seoul 03080, Korea.
SangYun KimDepartment of Neurology, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do 13620, Korea.
Byeong C KimDepartment of Neurology, Chonnam National University Medical School, Gwangju 61469, Korea.ORCID 0000-0001-6827-6730
Hoowon KimNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea.ORCID 0000-0001-5973-0559
Gyungah R JunDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118, USA.ORCID 0000-0002-3230-8697
Gerard D SchellenbergDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104-4238, USA.
Takeshi IkeuchiDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata 951-8585, Japan.ORCID 0000-0001-8828-8085
Lindsay A FarrerDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118, USA.
Kun Ho LeeNational Research Center for Dementia, Chosun University, Gwangju 61452, Korea. leekho@chosun.ac.kr.ORCID 0000-0003-4144-8162
Alzheimer's Disease Neuroimaging Initative
Chosun University · KRBoston University · USNiigata University · JPSeoul National University · KRSeoul National University Bundang Hospital · KRChonnam National University Hospital · KREwha Womans University · KRInha University · KRKyungpook National University · KRSeoul National University Hospital · KRCase Western Reserve University · USChosun University Hospital · KRChung-Ang University · KRColumbia University · USDong-A University · KRGachon University · KRGwangju Institute of Science and Technology · KRIndiana University School of MedicinePusan National University · KRThe Alfred Hospital · AU
Funding
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8MAlzheimer's Disease Genetics ConsortiumU01AG032984 · NIA · UNIVERSITY OF PENNSYLVANIA · PI SCHELLENBERG, GERARD DAVID · 2009 to 2024
$60.4MSUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1MEPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3MThe National Institute on Aging (NIA) Late Onset of Alzheimer's Disease (LOAD) Family-Based Study (FBS)U24AG056270 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gary Wayne Beecham, TATIANA M. FOROUD · 2017 to 2026
$31.4MGenetic Studies of Alzheimer's Disease in Caribbean HispanicsRF1AG015473 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P · 2015 to 2018
$3.3MIntegrating Neuroimaging, Multi-omics, and Clinical Data in Complex DiseaseR01LM012535 · NLM · INDIANA UNIVERSITY INDIANAPOLIS · PI NHO, KWANGSIK TIMOTHY · 2017 to 2021
$1.7MJapan Agency for Medical Research and Development JP18kk0205009National Research Foundation of Korea NRF-2014M3C7A1046041NIA NIH HHS P30 AG010161NIA NIH HHS R01 AG017917NIA NIH HHS R01-AG048927; P30-AG13846; U01-AG032984; RF1-AG057519NIA NIH HHS RF1 AG015473NIA NIH HHS U01 AG032984NIA NIH HHS U24 AG021886NIA NIH HHS U24 AG056270
Abstract
Variants in the
Indexed as
Alzheimer’s diseaseAPOEbrain atrophyethnic variabilitygenetic associationpromoter polymorphism
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.