Evidence map›Paper›PMID 31426298›Full record

ArticleMolecules (Basel, Switzerland)2019

Sabotage at the Powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in

Cristina Dallabona, Marianna Pioli, Giorgio Spadola, Nicolò Orsoni, Franco Bisceglie, Tiziana Lodi, Giorgio Pelosi, Francesco Maria Restivo, Francesca Degola

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Predicted Aflatoxin BToxins · 2021
    Review
  4. Sensitivity ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cristina DallabonaDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.
Marianna PioliDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.
Giorgio SpadolaDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.
Nicolò OrsoniDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.
Franco BisceglieDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.ORCID 0000-0001-9165-0356
Tiziana LodiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.
Giorgio PelosiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.
Francesco Maria RestivoDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy.ORCID 0000-0002-7210-0751
Francesca DegolaDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43123 Parma, Italy. francesca.degola@unipr.it.ORCID 0000-0002-3937-251X
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amongst the various approaches to contain aflatoxin contamination of feed and food commodities, the use of inhibitors of fungal growth and/or toxin biosynthesis is showing great promise for the implementation or the replacement of conventional pesticide-based strategies. Several inhibition mechanisms were found taking place at different levels in the biology of the aflatoxin-producing fungal species such as

Indexed as

Gene Expression Regulation, FungalAflatoxinsAntifungal AgentsAspergillus flavusBinding SitesElectron TransportElectron Transport Complex IIIFungal ProteinsMitochondriaModels, BiologicalMolecular Docking SimulationMultigene FamilyProtein BindingSaccharomyces cerevisiaeThiosemicarbazonesAflatoxinsAntifungal AgentsElectron Transport Complex IIIFungal ProteinsThiosemicarbazonesaflatoxin inhibitormitochondrionrespiratory chainyeast model system

Identifiers

PMID31426298
PMCPMC6719062
OpenAlexW2968013102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.