Evidence map›Paper›PMID 31426272›Full record

Trial reportMolecules (Basel, Switzerland)2019

A Novel Self-Emulsifying Drug Delivery System (SEDDS) Based on VESIsorb

Katharina Knaub, Tina Sartorius, Tanita Dharsono, Roland Wacker, Manfred Wilhelm, Christiane Schön

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06578455 (A Randomized, Open-Label, 4-Way Crossover, Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions), which is not on this map. Cited by 60 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 3 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06578455 phase1completednot on this mapstarted 2024, after this paper: background citation

A Randomized, Open-Label, 4-Way Crossover, Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions

TypeinterventionalSponsordsm-firmenich Switzerland AGRan2024 to 2024Enrolled32ConditionsCBD Pharmacokinetics, Healthy ParticipantsArmsCannabidiol (CBD) Powder, Cannabidiol 100 MG/ML [Epidiolex]
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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  11. Development andDrug delivery · 2026
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  19. Nanomaterials (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Katharina KnaubBioTeSys GmbH, Schelztorstr. 54-56, 73728 Esslingen, Germany.
Tina SartoriusBioTeSys GmbH, Schelztorstr. 54-56, 73728 Esslingen, Germany. t.sartorius@biotesys.de.ORCID 0000-0001-8222-5833
Tanita DharsonoBioTeSys GmbH, Schelztorstr. 54-56, 73728 Esslingen, Germany.
Roland WackerBioTeSys GmbH, Schelztorstr. 54-56, 73728 Esslingen, Germany.
Manfred WilhelmNatural and Economic Sciences, Department of Mathematics, Ulm University of Applied Sciences, Albert-Einstein-Allee 55, 89081 Ulm, Germany.ORCID 0000-0003-1740-467X
Christiane SchönBioTeSys GmbH, Schelztorstr. 54-56, 73728 Esslingen, Germany.ORCID 0000-0003-3787-5268
BioTeSys (Germany) · DETechnische Hochschule Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabidiol (CBD), a phytocannabinoid compound of

Indexed as

Administration, OralAdultAnalgesicsAnti-Anxiety AgentsArea Under CurveBiological AvailabilityCannabidiolCross-Over StudiesDouble-Blind MethodDrug Delivery SystemsEmulsifying AgentsFastingFemaleHealthy VolunteersHumansMaleAnalgesicsAnti-Anxiety AgentsCannabidiolEmulsifying AgentsbioavailabilitycannabidiolCannabis sativaCBDhemp extracthumanoral drug delivery systempharmacokineticSEDDS

Identifiers

PMID31426272
PMCPMC6720748
OpenAlexW2968181969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.