Evidence map›Paper›PMID 31426054›Full record

ArticlePediatric research2019

Long-term vs. recent-onset obesity: their contribution to cardiometabolic risk in adolescence.

Raquel Burrows, Paulina Correa-Burrows, José Rogan, Evaline Cheng, Estela Blanco, Sheila Gahagan

Abstract read
In one paragraph

Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raquel BurrowsInstituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Avda. El Líbano 5524, Macul. CP: 7830490, Santiago, Chile. rburrows@inta.uchile.cl.
Paulina Correa-BurrowsInstituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Avda. El Líbano 5524, Macul. CP: 7830490, Santiago, Chile.
José RoganDepartamento de Física, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
Evaline ChengDivision of Child Development and Community Health, University of California San Diego, La Jolla, CA, USA.
Estela BlancoDivision of Child Development and Community Health, University of California San Diego, La Jolla, CA, USA.
Sheila GahaganDivision of Child Development and Community Health, University of California San Diego, La Jolla, CA, USA.

Funding

Biopsychosocial Determinants of Adolescent Obesity/Cardiovascular RiskR01HL088530 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA · 2008 to 2017
$5.0M
NHLBI NIH HHS R01 HL088530
6 · The paper itself

Abstract

backgroundThe contribution of long-term vs. recent-onset obesity to cardiometabolic risk in adolescence remains controversial. Here, we aimed to investigate the association of time of onset and length of obesity with the cardiometabolic profile of adolescence.

methodsProspective study in 678 16-year-olds. BMI was measured at birth-1-5-10-16 years and BMI trajectories were interpolated using cubic splines. BMI > 2 SD at <6 years was defined as early obesity. Waist circumference (WC), blood pressure, lipid and glucose profiles were measured at 16 years. A cardiometabolic risk score was computed (MetS_score). According to the BMI trajectory, four groups were defined: participants who were never obese (NOB), participants with obesity during adolescence (recent-onset obese (ROB)), participants who were obese in early childhood but transitioned to normal/overweight as preadolescents (formerly obese (FOB)), and participants who were obese in early childhood and remained obese (persistently obese (POB)).

resultsROBs and POBs had significantly unhealthier cardiometabolic profile than NOBs. No differences were observed in the cardiometabolic profile of ROBs compared to POBs. Although FOBs had higher WC and MetS_score than NOBs, no differences were found in other biomarkers. FOBs were in healthier cardiometabolic condition than ROBs and POBs.

conclusionsBoth long-term and recent-onset obesity increase the cardiometabolic risk in adolescents.

Indexed as

AdolescentAge of OnsetCardiovascular DiseasesFemaleHumansMaleObesityProspective StudiesRisk Factors

Identifiers

PMID31426054
PMCPMC6891158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.