ArticleNeuroImage. Clinical2019
White matter microstructure correlates with mathematics but not word reading performance in 13-year-old children born very preterm and full-term.
Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Associations between mathematical skills and white matter microstructure in children born preterm.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2026Article
- Article
- Multi-view fusion of diffusion MRI microstructural models: a preterm birth study.Frontiers in neuroscience · 2024Article
- Perinatal influences on academic achievement and the developing brain: a scoping systematic review.Frontiers in psychology · 2024Article
- Spherical convolutional neural networks can improve brain microstructure estimation from diffusion MRI data.Frontiers in neuroimaging · 2024Article
- Increased white matter fibre dispersion and lower IQ scores in adults born preterm.Human brain mapping · 2024Article
- Neuroimaging of brain connectivity related to reading outcomes in children born preterm: A critical narrative review.Frontiers in pediatrics · 2023Review
- Advanced Brain Imaging in Preterm Infants: A Narrative Review of Microstructural and Connectomic Disruption.Children (Basel, Switzerland) · 2022Review
- Extracallosal Structural Connectivity Is Positively Associated With Language Performance in Well-Performing Children Born Extremely Preterm.Frontiers in pediatrics · 2022Article
- Neurite density and arborization is associated with reading skill and phonological processing in children.NeuroImage · 2021Article
- Development of brain white matter and math computation ability in children born very preterm and full-term.Developmental cognitive neuroscience · 2021Article
- Gestational Age at Term and Educational Outcomes at Age Nine.Pediatrics · 2021Article
- Diffusion magnetic resonance imaging assessment of regional white matter maturation in preterm neonates.Neuroradiology · 2021Article
- Cochlear implantation in prelingually deaf children with white matter lesions.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
- Cerebral White Matter Myelination and Relations to Age, Gender, and Cognition: A Selective Review.Frontiers in human neuroscience · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals born very preterm (VPT; <32 weeks' gestational age) are at increased risk of impaired mathematics and word reading performance, as well as widespread white matter microstructural alterations compared with individuals born full term (FT; ≥37 weeks' gestational age). To date, the link between academic performance and white matter microstructure is not well understood. This study aimed to investigate the associations between mathematics and reading performance with white matter microstructure in 114 VPT and 36 FT 13-year-old children. Additionally, we aimed to investigate whether the association of mathematics and reading performance with white matter microstructure in VPT children varied as a function of impairment. To do this, we used diffusion tensor imaging and advanced diffusion modelling techniques (Neurite Orientation Dispersion and Density Imaging and the Spherical Mean Technique), combined with a whole-brain analysis approach (Tract-Based Spatial Statistics). Mathematics performance across VPT and FT groups was positively associated with white matter microstructural measurements of fractional anisotropy and neurite density, and negatively associated with radial and mean diffusivities in widespread, bilateral regions. Furthermore, VPT children with a mathematics impairment (>1 standard deviation below FT mean) had significantly reduced neurite density compared with VPT children without an impairment. Reading performance was not significantly associated with any of the white matter microstructure parameters. Additionally, the associations between white matter microstructure and mathematics and reading performance did not differ significantly between VPT and FT groups. Our findings suggest that alterations in white matter microstructure, and more specifically lower neurite density, are associated with poorer mathematics performance in 13-year-old VPT and FT children. More research is required to understand the association between reading performance and white matter microstructure in 13-year-old children.
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