Evidence map›Paper›PMID 31425901›Full record

ArticleJournal of the neurological sciences2019

The dynamics of Poststroke depression among Ghanaians.

Fred Stephen Sarfo, Manolo Agbenorku, Sheila Adamu, Vida Obese, Patrick Berchie, Bruce Ovbiagele, PINGS Study investigators

Open access · greenAbstract read
In one paragraph

Article in Journal of the neurological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Long-term determinants of death after stroke in Ghana: Analysis by stroke types & subtypes.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  3. Key determinants of long-term post-stroke mortality in Ghana.Journal of the neurological sciences · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Fred Stephen SarfoDepartment of Medicine, Kwame Nkrumah University of Science & Technology, Kumasi, Ghana; Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana. Electronic address: stephensarfo78@gmail.com.
Manolo AgbenorkuDepartment of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Sheila AdamuDepartment of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Vida ObeseDepartment of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Patrick BerchieDepartment of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Bruce OvbiageleDepartment of Neurology, University of California, San Francisco, USA.
PINGS Study investigators
Komfo Anokye Teaching Hospital · GHUniversity of California, San Francisco · US

Funding

Phone-based Intervention Under Nurse Guidance after Stroke (PINGS)R21NS094033 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OVBIAGELE, BRUCE · 2015 to 2016
$337k
NINDS NIH HHS R21 NS094033
6 · The paper itself

Abstract

objectiveThe very few published data on post-stroke depression (PSD) among indigenous Africans have covered its prevalence and predictors. We sought to evaluate the dynamics of PSD in a cohort of Ghanaian stroke survivors followed for 9 months after an acute stroke.

methodsStroke survivors in this prospective cohort were adults aged >18 years with CT scan confirmed stroke, recruited into a randomized controlled trial to assess the feasibility of an mHealth technology-enabled, nurse guided intervention for blood pressure control. PSD was assessed a secondary outcome measure using the Hamilton Depression Rating Scale (HDRS) at enrollment, months 3, 6, and 9. Those with a score of >7 points on HDRS were categorized as depressed. A multivariate logistic regression analysis was performed to identify independent predictors of PSF.

resultsMean age of study participants was 55.1 ± 12.7 years with 65% being males. Ischemic strokes comprised 76.6% of study population. Prevalence of PSD at baseline was 78.6%, 43.6% at month 3, 41.1% at month 6 and 18.2% at month 9 (p < .0001). Factors significantly associated with PSD at baseline were higher NIH Stoke Scale score (adjusted OR 1.51, 95% CI: 1.03-2.23) and pain (adjusted OR 7.18, 95% CI: 1.52-33.89). NIHSS score (adjusted OR, 1.99, 95% CI: 1.12-3.52) as associated with PSD at month 9.

conclusion80% Ghanaian stroke survivors have early PSD declining to 20% at month 9. Stroke severity is the persistent factor associated with PSD at baseline and follow-up, and good be a target for screening and promptly treating PSD.

Indexed as

ComorbidityDepressionFemaleGhanaHumansMaleMiddle AgedProspective StudiesRisk FactorsStrokeTime FactorsFluoxetineGhanaPost-stroke depressionRisk factorsStroke severity

Identifiers

PMID31425901
PMCPMC6825566
OpenAlexW2964315879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.