Evidence map›Paper›PMID 31425524›Full record

SynthesisPloS one2019

A need for implementation science to optimise the use of evidence-based interventions in HIV care: A systematic literature review.

Joseph Cox, Cassidy Gutner, Nadine Kronfli, Anna Lawson, Michele Robbins, Lisette Nientker, Amrita Ostawal, Tristan Barber, Davide Croce, David Hardy and 7 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Navigating grey areas in HIV and mental health implementation science.Journal of the International AIDS Society · 2024
    Article
  8. Article
  9. Article
  10. Implementation determinants of HIV Self-Testing among young sexual minority men.Archives of public health = Archives belges de sante publique · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 8 countries.

Joseph CoxDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Canada.
Cassidy GutnerViiV Healthcare, London, England, United Kingdom.
Nadine KronfliDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Canada.
Anna LawsonViiV Healthcare, London, England, United Kingdom.
Michele RobbinsViiV Healthcare, London, England, United Kingdom.
Lisette NientkerPharmerit International, Rotterdam, the Netherlands.
Amrita OstawalPharmerit International, Berlin, Germany.
Tristan BarberChelsea and Westminster Hospital, London, England, United Kingdom.ORCID 0000-0003-1914-4891
Davide CroceUniversità Cattaneo LIUC, Castellanza, Italy.
David HardyWhitman-Walker Centre, Washington, DC, United States of America.
Heiko JessenPraxis Jessen, Berlin, Germany.
Christine KatlamaHôspital Universitaire Pitié-Salpêtrière, Paris, France.
Josep MallolasHospital Clinic, Barcelona, Spain.
Giuliano RizzardiniOspedale Sacco, Milan, Italy.
Keith AlcornNAM publications, London, England, United Kingdom.
Michael WohlfeilerAHF Clinics, Los Angeles/Miami, United States of America.
Eric Le FevreViiV Healthcare, London, England, United Kingdom.ORCID 0000-0003-3311-4306
ViiV Healthcare (United Kingdom) · GBMcGill University Health Centre · CAChelsea and Westminster Hospital · GBHospital Clínic de Barcelona · ESLuigi Sacco Hospital · ITOrthopädische Praxis · DEPharmerit (Netherlands) · NLSorbonne Université · FRUniversity Carlo Cattaneo · ITWhitman-Walker Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve health outcomes in people living with HIV, adoption of evidence-based interventions (EBIs) using effective and transferable implementation strategies to optimise the delivery of healthcare is needed. ViiV Healthcare's Positive Pathways initiative was established to support the UNAIDS 90-90-90 goals. A compendium of EBIs was developed to address gaps within the HIV care continuum, yet it was unknown whether efforts existed to adapt and implement these EBIs across diverse clinical contexts. Therefore, this review sought to report on the use of implementation science in adapting HIV continuum of care EBIs. A systematic literature review was undertaken to summarise the evaluation of implementation and effectiveness outcomes, and report on the use of implementation science in HIV care. Ten databases were reviewed to identify studies (time-period: 2013-2018; geographic scope: United States, United Kingdom, France, Germany, Italy, Spain, Canada, Australia and Europe; English only publications). Studies were included if they reported on people living with HIV or those at risk of acquiring HIV and used interventions consistent with the EBIs. A broad range of study designs and methods were searched, including hybrid designs. Overall, 118 publications covering 225 interventions consistent with the EBIs were identified. These interventions were evaluated on implementation (N = 183), effectiveness (N = 81), or both outcomes (N = 39). High variability in the methodological approaches was observed. Implementation outcomes were frequently evaluated but use of theoretical frameworks was limited (N = 13). Evaluations undertaken to assess effectiveness were inconsistent, resulting in a range of measures. This review revealed extensive reporting on implementation science as defined using evaluation outcomes. However, high variability was observed in how implementation outcomes and effectiveness were defined, quantified, and reported. A more specific and consistent approach to conducting and reporting on implementation science in HIV could facilitate achievement of UNAIDS 90-90-90 targets.

Indexed as

Continuity of Patient CareDelivery of Health CareEvidence-Based MedicineHIV InfectionsHumansOutcome Assessment, Health CareSustained Virologic ResponseUnited Nations

Identifiers

PMID31425524
PMCPMC6699703
OpenAlexW2969469570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.