Evidence map›Paper›PMID 31425513›Full record

ArticlePLoS neglected tropical diseases2019

The diagnosis of scabies by non-expert examiners: A study of diagnostic accuracy.

Millicent H Osti, Oliver Sokana, Christina Gorae, Margot J Whitfeld, Andrew C Steer, Daniel Engelman

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Scabies.Nature reviews. Disease primers · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Health-related quality of life impact of scabies in the Solomon Islands.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
    Article
  16. Article
  17. A framework for scabies control.PLoS neglected tropical diseases · 2021
    Article
  18. Article
  19. Paediatrics: how to manage scabies.Drugs in context · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Millicent H OstiTropical Diseases, Murdoch Children's Research Institute, Melbourne, VIC, Australia.ORCID 0000-0002-0588-9238
Oliver SokanaMinistry of Health and Medical Services, Honiara, Solomon Islands.
Christina GoraeMinistry of Health and Medical Services, Honiara, Solomon Islands.
Margot J WhitfeldDepartment of Dermatology, St Vincent's Hospital, Sydney, NSW, Australia.
Andrew C SteerTropical Diseases, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
Daniel EngelmanTropical Diseases, Murdoch Children's Research Institute, Melbourne, VIC, Australia.ORCID 0000-0002-4909-1287
Royal Children's Hospital · AUThe University of Melbourne · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough scabies is estimated to be one of the most common skin conditions globally, prevalence data is not available in most settings. Disease mapping is required to develop and monitor successful control programs. Non-expert health workers are likely to play an important role in scabies mapping activities in endemic settings. METHODOLOGY: Four non-expert health workers were trained in the diagnosis of scabies and impetigo. The health worker diagnosis was compared to a reference consensus diagnosis of two doctors experienced in diagnosis. The study was conducted in a primary school in Gizo, Solomon Islands, in August 2018. The six examiners consecutively assessed school students, blinded to each other's findings. Training and diagnostic procedures followed criteria for scabies diagnosis established by the International Alliance for the Control of Scabies in 2018. PRINCIPAL

findingsAmongst the 171 students who underwent clinical assessment the prevalence of scabies and impetigo according to the reference standard was 55% and 45% respectively. Sensitivity of the non-expert health workers' diagnosis compared to the reference standard was 55.3% for scabies (95% confidence interval [CI], 50.1-60.4) with a specificity of 89.9% (95% CI 86-93.1) and 52.6% for impetigo (95% CI 46.9-58.3) with a specificity 97.8% (95% CI 95.7-99). Sensitivity for moderate to severe scabies was 93.5% (95% CI 86.3-97.6) with a specificity of 74% (95% CI 70.2-77.5).

conclusionsFollowing brief training, the diagnostic accuracy of non-expert health workers for scabies and impetigo was promising, especially for moderate to severe disease. Modifications to training and processes are recommended to further improve accuracy. The diagnosis by non-expert health workers may be acceptable for scabies and impetigo mapping in endemic areas.

Indexed as

Community Health WorkersAdolescentChildChild, PreschoolDiagnostic Tests, RoutineFemaleHumansImpetigoMaleMelanesiaProspective StudiesScabiesSchoolsSensitivity and Specificity

Identifiers

PMID31425513
PMCPMC6715246
OpenAlexW2969600525

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.