ArticleGenome biology and evolution2019
Expressed Vomeronasal Type-1 Receptors (V1rs) in Bats Uncover Conserved Sequences Underlying Social Chemical Signaling.
Article in Genome biology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Different Species of Bats: Genomics, Transcriptome, and Immune Repertoire.Current issues in molecular biology · 2025Review
- Gene expression comparisons between captive and wild shrew brains reveal captivity effects.Biology letters · 2025Article
- Placing human gene families into their evolutionary context.Human genomics · 2022Review
- Coding of pheromones by vomeronasal receptors.Cell and tissue research · 2021Review
- Do bats use guano and urine stains to find new roosts? Tests with three group-living bats.Royal Society open science · 2020Article
- Distinct evolutionary trajectories of V1R clades across mouse species.BMC evolutionary biology · 2020Article
- Comparative genomic analyses illuminate the distinct evolution of megabats within Chiroptera.DNA research : an international journal for rapid publication of reports on genes and genomes · 2020Article
- Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals.Genome biology and evolution · 2020Article
- Evolutionary ecology of chemosensation and its role in sensory drive.Current zoology · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In mammals, social and reproductive behaviors are mediated by chemical cues encoded by hyperdiverse families of receptors expressed in the vomeronasal organ. Between species, the number of intact receptors can vary by orders of magnitude. However, the evolutionary processes behind variation in receptor number, and its link to fitness-related behaviors are not well understood. From vomeronasal transcriptomes, we discovered the first evidence of intact vomeronasal type-1 receptor (V1r) genes in bats, and we tested whether putatively functional bat receptors were orthologous to those of related taxa, or whether bats have evolved novel receptors. Instead of lineage-specific duplications, we found that bat V1rs show high levels of orthology to those of their relatives, and receptors are under comparative levels of purifying selection as non-bats. Despite widespread vomeronasal organ loss in bats, V1r copies have been retained for >65 million years. The highly conserved nature of bat V1rs challenges our current understanding of mammalian V1r function and suggests roles other than conspecific recognition or mating initiation in social behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.