Evidence map›Paper›PMID 31424460›Full record

Trial reportOncology nursing forum2019

Temporary Stoppages and Burden of Treatment in Patients With Cancer.

Eric Vachon, Barbara Given, Charles Given, Susann Dunn

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Oncology nursing forum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Self-care behaviors in patients with cancer treated with oral anticancer agents: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  3. Observational
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eric VachonMichigan State University.ORCID 0000-0002-3181-8337
Barbara GivenMichigan State University.
Charles GivenMichigan State University.
Susann DunnUniversity of Illinois.

Funding

Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVRR01CA162401 · NCI · MICHIGAN STATE UNIVERSITY · PI GIVEN, BARBARA ANN, GIVEN, CHARLES W · 2013 to 2016
$2.3M
NCI NIH HHS R01 CA162401
6 · The paper itself

Abstract

objectivesTo examine the effect of burden of treatment and multimorbidity on the relationship between baseline characteristics and oral oncolytic agent (OOA) temporary stoppages. SAMPLE &

setting272 patients newly prescribed OOAs at six National Cancer Institute-designated comprehensive cancer centers. METHODS & VARIABLES: Patients were randomly assigned to an adherence and symptom management group or a usual care/control group. Temporary OOA stoppages, symptom interference, OOA regimen complexity, and multimorbidities were explored. Data were collected at four-week intervals for 12 weeks.

resultsBurden of treatment variables and multimorbidity had no significant effect on OOA temporary stoppages. Women and those prescribed kinase inhibitors were significantly more likely to experience a temporary stoppage. IMPLICATIONS FOR NURSING: Oncology nurses are in a crucial position to educate patients on self-management of OOAs and symptoms. Nurses should be aware of patients who may be more susceptible to severe symptoms, including those with multimorbidities. Future research is needed to better understand OOA stoppages and factors associated with preventing stoppages.

Indexed as

Medication AdherenceReminder SystemsAgedAntineoplastic AgentsAutomationComorbidityDrug Administration ScheduleFemaleHumansMaleMiddle AgedNeoplasmsPolypharmacySelf AdministrationSelf CareSymptom AssessmentAntineoplastic Agentsburden of treatmentmultimorbid conditionsoral oncolytic agentstreatment interruption

Identifiers

PMID31424460
PMCPMC7360060

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.