Evidence map›Paper›PMID 31424089›Full record

ArticleBiometrics2020

Biclustering via sparse clustering.

Erika S Helgeson, Qian Liu, Guanhua Chen, Michael R Kosorok, Eric Bair

Abstract readComparative Study
In one paragraph

Article in Biometrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Moderator effect of sex in the clustering of treatment-seeking patients with gambling problems.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erika S HelgesonDivision of Biostatistics, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0001-5170-7100
Qian LiuDepartment of Biostatistics, University of North Carolina, Chapel Hill, North Carolina.
Guanhua ChenDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin.ORCID 0000-0002-9314-2037
Michael R KosorokDepartment of Biostatistics, University of North Carolina, Chapel Hill, North Carolina.ORCID 0000-0002-6070-9738
Eric BairDepartments of Endodontics and Biostatistics, University of North Carolina, Chapel Hill, North Carolina.

Funding

UNC CLINICAL AND TRANSLATIONAL SCIENCE AWARD: BPCAUL1RR025747 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$44.6M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Statistical Methods for Cancer Clinical TrialsP01CA142538 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIDIAN, MARIE, KOSOROK, MICHAEL R · 2010 to 2019
$21.3M
Identification of Clinically Relevant TMD Subtypes Using Cluster AnalysisR03DE023592 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BAIR, ERIC · 2013 to 2014
$293k
NCI NIH HHS P01 CA142538NCRR NIH HHS UL1 RR025747NIDCR NIH HHS R03 DE023592NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

In identifying subgroups of a heterogeneous disease or condition, it is often desirable to identify both the observations and the features which differ between subgroups. For instance, it may be that there is a subgroup of individuals with a certain disease who differ from the rest of the population based on the expression profile for only a subset of genes. Identifying the subgroup of patients and subset of genes could lead to better-targeted therapy. We can represent the subgroup of individuals and genes as a bicluster, a submatrix,

Indexed as

AlgorithmsCluster AnalysisAnalysis of VarianceBiometryComputer SimulationData Interpretation, StatisticalDiseaseHumansModels, StatisticalNormal DistributionSoftwareTemporomandibular Joint Disordersbiclusteringhierarchical clusteringhigh-dimensional datak-means clusteringsparse clustering

Identifiers

PMID31424089
PMCPMC7028479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.