Evidence map›Paper›PMID 31424019›Full record

ArticleIndian journal of medical microbiology

Use of TaqMan Array card for the detection of respiratory viral pathogens in children under 5 years old hospitalised with acute medical illness in Ballabgarh, Haryana, India.

Bharti Gaur, Siddhartha Saha, A Danielle Iuliano, Sanjay K Rai, Anand Krishnan, Seema Jain, Brett Whitaker, Jonas Winchell, Renu B Lal, Shobha Broor

Abstract read
In one paragraph

Article in Indian journal of medical microbiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Open forum infectious diseases · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bharti GaurDepartment of Microbiology, All Institute of Medical Sciences, New Delhi, India.
Siddhartha SahaInfluenza Division, Centers for Disease Control and Prevention, U.S Embassy, New Delhi, India.
A Danielle IulianoInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sanjay K RaiCentre for Community Medicine, All Institute of Medical Sciences, New Delhi, India.
Anand KrishnanCentre for Community Medicine, All Institute of Medical Sciences, New Delhi, India.
Seema JainInfluenza Division, Centers for Disease Control and Prevention, U.S Embassy, New Delhi, India.
Brett WhitakerDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jonas WinchellDivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Renu B LalInfluenza Division, Centers for Disease Control and Prevention, U.S Embassy, New Delhi, India.
Shobha BroorDepartment of Microbiology, All Institute of Medical Sciences, New Delhi, India.

Funding

Intramural CDC HHS CC999999NCIRD CDC HHS U01 IP000206
6 · The paper itself

Abstract

Historical specimens collected from hospitalized children were tested for the following 13 viruses: influenza A and B; respiratory syncytial virus (RSV); parainfluenza viruses 1-3; human metapneumovirus; rhinovirus; coronaviruses 229E, OC43, NL63 and HKU1 and Adenovirus using monoplex real-time reverse transcriptase polymerase chain reaction (rRT-PCR). They were retested using TaqMan Array Card (TAC), a micro-fluidic system, capable of simultaneous multi-pathogen testing, to evaluate its sensitivity and specificity against monoplex rRT-PCR. TAC showed high sensitivity (71%-100%) and specificity (98%-100%) for these viruses in comparison to monoplex rRT-PCR. Multi-specimen detection with high sensitivity and specificity makes TAC a potentially useful tool for both surveillance and outbreak investigations.

Indexed as

Lab-On-A-Chip DevicesChild, PreschoolHumansIndiaInfantInfant, NewbornMicrofluidic Analytical TechniquesMolecular Diagnostic TechniquesReal-Time Polymerase Chain ReactionRespiratory Tract InfectionsSensitivity and SpecificityVirusesMicro-fluidic cardsensitivityspecificityviral pathogen diagnosis

Identifiers

PMID31424019
PMCPMC9257431

What OpenQuestion holds

Textmetadata
LicenceCC BY-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.