Evidence map›Paper›PMID 31423930›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

The mass transfer coefficient for oxygen transport from blood to tissue in cerebral cortex.

Timothy W Secomb, Katherine V Bullock, David A Boas, Sava Sakadžić

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  10. Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Timothy W SecombDepartment of Physiology, University of Arizona, Tucson, AZ, USA.ORCID 0000-0002-0176-5502
Katherine V BullockPhysiological Sciences Graduate Program, University of Arizona, Tucson, AZ, USA.
David A BoasAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Sava SakadžićAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
University of Arizona · USBoston University · USHarvard University · US

Funding

Targeting ROCK for Neurogliovascular Plasticity & Remodeling After StrokeP01NS055104 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI LO, ENG H. · 2007 to 2018
$13.3M
MICROSCOPIC FOUNDATION OF MULTIMODAL HUMAN IMAGINGR01MH111359 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DALE, ANDERS M, DEVOR, ANNA · 2016 to 2020
$5.6M
Two-Photon Microscopy of Oxygen Consumption in the BrainR01NS091230 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI SAKADZIC, SAVA · 2015 to 2019
$2.4M
Multiscale modeling of cerebral blood flow and oxygen transportU01HL133362 · NHLBI · UNIVERSITY OF ARIZONA · PI SECOMB, TIMOTHY W. · 2017 to 2021
$2.0M
Oxygen imaging by phosphorescence quenchingU24EB028941 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI VINOGRADOV, SERGEI · 2019 to 2023
$1.6M
NHLBI NIH HHS U01 HL133362NIBIB NIH HHS U24 EB028941NINDS NIH HHS P01 NS055104NINDS NIH HHS R01 NS091230
6 · The paper itself

Abstract

The functioning of cerebral cortex depends on adequate tissue oxygenation. MRI-based techniques allow estimation of blood oxygen levels, tissue perfusion, and oxygen consumption rate (CMRO

Indexed as

Models, BiologicalAnimalsCerebral CortexDiffusionHumansMicrocirculationMicrovesselsOxygenOxygen ConsumptionOxygenCapillary densityhematocritmagnetic resonance imagingoxygen transporttheoretical models

Identifiers

PMID31423930
PMCPMC7370375
OpenAlexW2969989723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.