ArticleJournal of investigative medicine high impact case reports
Severe Persistent Hyponatremia: A Rare Presentation of Biliary Fluid Loss.
Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Acute Hyponatremia as a Telling Complication of Necrotizing Pancreatitis and Perforated Cholecystitis After Percutaneous Cholecystostomy.ACG case reports journal · 2026Article
- Severe hyponatraemia due to high output external biliary drainage corrected with bile refeeding: A case report.SAGE open medical case reports · 2024Article
- Metallic stent placement versus catheter drainage for malignant bilioenteric anastomotic stricture.Japanese journal of radiology · 2022Article
- Occurrence and clinical relevance of postoperative hypernatremia in dogs undergoing cholecystectomy.Journal of veterinary internal medicineArticle
- Exploring Bariatric Surgery's Impact on Weight Loss and Diabetes: Sodium and Glucose Receptor Modulation.JSLS : Journal of the Society of Laparoendoscopic SurgeonsReview
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypotonic hyponatremia is caused by a serum sodium level of <135 mEq/L in the setting of excess solute loss accompanied by free water retention because of antidiuretic hormone release, subsequent to decreased effective arterial blood volume. Acute hyponatremia can have various neurological manifestations, including drowsiness, lethargy, coma, seizures, respiratory depression, and even death. In this article, we present a case of a 41-year-old man who presented with hyponatremia as a result of sodium containing biliary fluid loss and resultant renal free water retention in response to increased antidiuretic hormone secretion. He underwent placement of a cholecystostomy tube for acalculous cholecystitis and was found to be persistently hyponatremic despite repletion with sodium-containing fluids. Once the cholecystostomy tube was removed, the patient's sodium levels improved, and his symptoms resolved. Our case highlights choleuresis as an unusual but significant cause of hyponatremia in patients who have external biliary drainage.
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