Evidence map›Paper›PMID 31423549›Full record

ArticleClinical and experimental nephrology2019

Acute effect of a peritoneal dialysis exchange on electrolyte concentration and QT interval in uraemic patients.

Simonetta Genovesi, Elisa Nava, Chiara Bartolucci, Stefano Severi, Antonio Vincenti, Gina Contaldo, Giada Bigatti, Daniele Ciurlino, Silvio Volmer Bertoli

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Sources of QTc variability: Implications for effective ECG monitoring in clinical practice.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Simonetta GenovesiDepartment Medicine and Surgery, University of Milan-Bicocca, Via Cadore 48, 20900, Monza, Italy. simonetta.genovesi@unimib.it.
Elisa NavaDepartment Medicine and Surgery, University of Milan-Bicocca, Via Cadore 48, 20900, Monza, Italy.
Chiara BartolucciComputational Physiopathology Unit Department of Electrical, Electronic and Information Engineering "Guglielmo Marconi", University of Bologna, Via dell'Università 50, 47522, Cesena, Italy.
Stefano SeveriComputational Physiopathology Unit Department of Electrical, Electronic and Information Engineering "Guglielmo Marconi", University of Bologna, Via dell'Università 50, 47522, Cesena, Italy.
Antonio VincentiDepartment of Cardiology, Ospedale San Giuseppe Multimedica, Via San Vittore 12, 20123, Milan, Italy.
Gina ContaldoDepartment Medicine and Surgery, University of Milan-Bicocca, Via Cadore 48, 20900, Monza, Italy.
Giada BigattiDialysis and Nephrology Unit, IRCCS Multimedica, Via Milanese 300, 20099, Sesto San Giovanni, Italy.
Daniele CiurlinoDialysis and Nephrology Unit, IRCCS Multimedica, Via Milanese 300, 20099, Sesto San Giovanni, Italy.
Silvio Volmer BertoliDialysis and Nephrology Unit, IRCCS Multimedica, Via Milanese 300, 20099, Sesto San Giovanni, Italy.
MultiMedica · ITUniversity of Milano-Bicocca · ITUniversity of Bologna · ITOspedale San Giuseppe · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemodialysis (HD) sessions induce changes in plasma electrolytes that lead to modifications of QT interval, virtually associated with dangerous arrhythmias. It is not known whether such a phenomenon occurs even during peritoneal dialysis (PD). The aim of the study is to analyze the relationship between dialysate and plasma electrolyte modifications and QT interval during a PD exchange.

methodsIn 15 patients, two manual PD 4-h exchanges were performed, using two isotonic solutions with different calcium concentration (Ca

resultsDialysis exchange induced a significant plasma alkalizing effect (p < 0.001). Plasma K

conclusionsThe PD exchange guarantees a greater cardiac electrical stability compared to the HD session and should be preferred in patients with a higher arrhythmic risk. Moreover, our study shows that ventricular repolarization is extremely sensitive to plasma K

Indexed as

Peritoneal DialysisAgedAged, 80 and overCalciumComputer SimulationDialysis SolutionsElectrocardiography, AmbulatoryElectrolytesFemaleHeart RateHumansIsotonic SolutionsKidney Failure, ChronicMaleMiddle AgedPotassiumCalciumDialysis SolutionsElectrolytesIsotonic SolutionsPotassiumSodiumArrhythmiasComputational modelElectrolytesPeritoneal dialysisQT interval

Identifiers

PMID31423549
OpenAlexW2969402515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.