ReviewEFORT open reviews2019
Periprosthetic joint infection: current concepts and outlook.
Review in EFORT open reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 361 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
361 citing papers in PubMed, 6 syntheses or guidelines pooled it, 580 citations in OpenAlex.
- Is synovial calprotectin lateral flow test a reliable intraoperative biomarker for periprosthetic joint infection? A systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2026Pooled it
- Diagnostic accuracy of the monocyte-to-lymphocyte ratio in periprosthetic joint infection: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2025Pooled it
- A systematic review and meta-analysis on the effects of intravenous dexamethasone on postoperative outcomes in patients undergoing total knee arthroplasty.Langenbeck's archives of surgery · 2025Pooled it
- Incidence of periprosthetic joint infection after primary total knee arthroplasty shows significant variation : a synthesis of meta-analysis and bibliometric analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Corynebacterium periprosthetic joint infection: a systematic review of 52 cases at 2.5 years follow-up.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Natural history of changes in knee skin temperature following total knee arthroplasty: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Diagnostic Value of Synovial Fluid Biomarkers for Periprosthetic Joint Infection: A Prospective, Double-blind Trial.Medical science monitor : international medical journal of experimental and clinical research · 2023Trial
- DVIA technique for acute periprosthetic joint infection: a surgical technique and case series.Arthroplasty (London, England) · 2026Article
- Comparative effectiveness of single-stage versus two-stage revision for hip prosthetic joint infection: emulation of the INFORM target trial using electronic health record data.Archives of orthopaedic and trauma surgery · 2026Observational
- Decoding resistance: a comprehensive study on pathogens and antibiotic efficacy in periprosthetic joint infections.Journal of orthopaedic surgery and research · 2026Article
- A target-based population pharmacokinetic and pharmacodynamic analysis for intra-articular dosing regimen optimization of vancomycin in patients with periprosthetic joint infections.Bone & joint research · 2026Article
- Outcome of guided persistent fistula as a salvage procedure in patients with chronic periprosthetic joint infection.International orthopaedics · 2026Article
- Octenidine-Based Versus Chlorhexidine-Based Preoperative Skin Antisepsis in Primary Hip and Knee Arthroplasty.Arthroplasty today · 2026Article
- Does Aspiration With Culture Augmented With Percutaneous Core Biopsy Analysis Have Better Diagnostic Value Than Culture Alone for PJI in Large Joints? A Prospective Enhancement and Feasibility Study.Clinical orthopaedics and related research · 2026Article
- Infection prevention in total knee arthroplasty: current concepts, controversies, and a clinical algorithm.European journal of translational myology · 2026Article
- Ultrasound combined with voriconazole for treating acute fungal periprosthetic joint infection caused by Candida albicans : an in vitro and in vivo experimental study.Bone & joint research · 2026Article
- Prolonged linezolid therapy induces progressive mitochondrial dysfunction in human peripheral blood mononuclear cells.Journal of translational medicine · 2026Article
- Article
- Impact of Infection Timing on Outcomes: A Comparative Study of Periprosthetic Joint and Fracture-Related Infections.Orthopaedic surgery · 2026Article
- Does spacer type influence bone lysis and clinical outcomes? A comparative analysis in two-stage revision for periprosthetic knee infection.BMC surgery · 2026Observational
301 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periprosthetic joint infection (PJI) is a serious complication occurring in 1% to 2% of primary arthroplasties, which is associated with high morbidity and need for complex interdisciplinary treatment strategies.The challenge in the management of PJI is the persistence of micro-organisms on the implant surface in the form of biofilm. Understanding this ability, the phases of biofilm formation, antimicrobial susceptibility and the limitations of host local immune response allows an individual choice of the most suitable treatment.By using diagnostic methods for biofilm detection such as sonication, the sensitivity for diagnosing PJI is increasing, especially in chronic infections caused by low-virulence pathogens.The use of biofilm-active antibiotics enables eradication of micro-organisms in the presence of a foreign body. The total duration of antibiotic treatment following revision surgery should not exceed 12 weeks. Cite this article:
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.