Evidence map›Paper›PMID 31423310›Full record

ArticleMolecular and clinical oncology2019

The association between statins and colorectal cancer stage in the Women's Health Initiative.

Brian P Rutledge, Pinkal Desai, Simin Liu, Juhua Luo, Rami Nassir, Qi Lihong, Monica Arun, Mahmoud Abdel-Rasoul, Michael S Simon

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Brian P RutledgeDepartment of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Pinkal DesaiDepartment of Hematology and Medical Oncology Weill Cornell Medical College, New York, NY 10065, USA.
Simin LiuThe Alpert School of Medicine, Center for Global Cardiometabolic Heath, and School of Public Health, Brown University, Providence, RI 02093, USA.
Juhua LuoSchool of Public Health, Indiana University, Bloomington, IN 47405, USA.
Rami NassirDepartment of Biochemistry and Molecular Medicine, University of California, Davis, CA 95817, USA.
Qi LihongDepartment of Public Health Sciences, University of California, Davis, CA 95817, USA.
Monica ArunDepartment of Internal Medicine, Division of Hematology and Onology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Mahmoud Abdel-RasoulDepartment of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH 43201, USA.
Michael S SimonDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.
University of California, Davis · USBrown University · USCornell University · USIndiana University Bloomington · USThe Barbara Ann Karmanos Cancer Institute · USThe Ohio State University · USUniversity of Michigan–Ann Arbor · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anticarcinogenic effect of statins may reduce the metastatic potential of cancer cells leading to 'stage migration', with users more likely diagnosed with early rather than late stage cancer. The association between prior statin use and colorectal cancer (CRC) stage at diagnosis in the Women's Health Initiative (WHI) was investigated. The study population included 132,322 post-menopausal women, among which there were 2,628 pathologically confirmed cases of

Indexed as

colorectal neoplasmhydrophilichydrophobichydroxymethylglutaryl-CoA reductase inhibitorsneoplasm staging

Identifiers

PMID31423310
PMCPMC6688425
OpenAlexW2954029226

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.