Evidence map›Paper›PMID 31423180›Full record

ArticleOncology letters2019

Interactive online consensus survival tool for esophageal squamous cell carcinoma prognosis analysis.

Qiang Wang, Fengling Wang, Jiajia Lv, Junfang Xin, Longxiang Xie, Wan Zhu, Yitai Tang, Yongqiang Li, Xiaofang Zhao, Yunlong Wang and 2 more

Abstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Roles of long non-coding RNAs in oesophageal cancer pathogenesis.International journal of experimental pathology · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. The Partial Role of KLF4 and KLF5 in Gastrointestinal Tumors.Gastroenterology research and practice · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Identification of Autophagy-Related Genes and Small-Molecule Drugs in Esophageal Carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qiang WangDepartment of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.
Fengling WangDepartment of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.
Jiajia LvDepartment of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.
Junfang XinDepartment of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.
Longxiang XieDepartment of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.
Wan ZhuDepartment of Anesthesia, Stanford University, Stanford, CA 94305, USA.
Yitai TangDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Yongqiang LiDepartment of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.
Xiaofang ZhaoJiangsu SuperBio Co., Ltd., Nanjing, Jiangsu 210061, P.R. China.
Yunlong WangHenan Bioengineering Research Center, Zhengzhou, Henan 450046, P.R. China.
Xianzhe LiDepartment of Thoracic Surgery, The Affiliated Nanshi Hospital of Henan University, Nanyang, Henan 473003, P.R. China.
Xiangqian GuoDepartment of Preventive Medicine, Institute of Biomedical Informatics, Bioinformatics Center, Cell Signal Transduction Laboratory, School of Software, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous cell carcinoma (ESCC) is one of the most common types of cancer worldwide. However, operative diagnostic and prognostic systems for ESCC remain to be established. To improve assessment of the prognosis for patients with ESCC, the present study developed an online consensus survival tool for ESCC, termed OSescc. OSescc was built using 264 ESCC cases with gene expression data and relevant clinical information obtained from the Gene Expression Omnibus and The Cancer Genome Atlas databases. Kaplan-Meier survival plots with hazard ratios and P-values were generated by OSescc to predict the association between potential biomarkers and relapse free survival and overall survival. In addition, the current study integrated a function by which one could assess the prognosis based on an individual probe or the mean value of multiple probes for each gene, which helped improve the evaluation of the validity and reliability of the potential prognosis biomarkers. OSescc can be accessed at bioinfo.henu.edu.cn/DBList.jsp.

Indexed as

databaseesophageal squamous cell carcinomaprognosissurvivaltool

Identifiers

PMID31423180
PMCPMC6607102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.