Comparative Analysis of Mean Pleural Fluid D-dimer Level in Malignant and Non-Malignant Pleural Effusion Patients.

Mohammad Emami Ardestani, Mohammad Modaemzadeh, Ali Reza Mohammadi

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Article in Tanaffos, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 authors at 1 institution in 1 country.

Mohammad Emami ArdestaniDepartments of Pulmonology, Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Mohammad ModaemzadehInternal Medicine Department, Isfahan University of Medical Sciences, Isfahan, Iran.

Ali Reza MohammadiIsfahan University of Medical Sciences, Isfahan, Iran.

Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalignant Pleural Effusion (MPE) is a condition that mostly presents with dyspnea. There are some ways to distinguish it from Non-Malignant Pleural Effusion (NMPE).The aim of this study was to compare serum and pleural D-dimer levels between MPE and NMPE patients. MATERIALS AND

methodsPatients diagnosed with Pleural Effusion (PE) were selected to participate in this study. They were allocated in 2 groups of MPE and NMPE according to the etiology. Serum and pleural fluid D-dimer level were measured and statistically analyzed between two groups.

results32 MPE patients and 32 NMPE patients participated in this study. The mean age was 61.3 ± 12 years and M/F ratio was 35/29. The mean pleural and serum D-dimer levels were 3472± 1312 ng/dl and 3259±1220 ng/dl in patients with MPE, and 3425 ± 32.5ng/dl and 2425 ± 1311ng/dl in patients with NMPE, respectively. The serum D-dimer levels were not statistically different between 2 groups; while the pleural D-dimer levels were higher in MPE group in comparison with NMP patients (P<0.05).

conclusionThis study showed that pleural D-dimer levels were significantly different between two groups and therefore pleural D-dimer can be considered as a non-invasive tool for diagnosis of MPE.

Indexed as

D-dimerMalignancyPleural effusion

Identifiers

PMID31423140

PMCPMC6690320

OpenAlexW2986792322

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