Evidence map›Paper›PMID 31423009›Full record

ArticleScientific reports2019

Increase Trichomonas vaginalis detection based on urine routine analysis through a machine learning approach.

Hsin-Yao Wang, Chung-Chih Hung, Chun-Hsien Chen, Tzong-Yi Lee, Kai-Yao Huang, Hsiao-Chen Ning, Nan-Chang Lai, Ming-Hsiu Tsai, Li-Chuan Lu, Yi-Ju Tseng and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Review
  7. Review
  8. Economic evaluations of big data analytics for clinical decision-making: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hsin-Yao WangDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Chung-Chih HungDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Chun-Hsien ChenDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Tzong-Yi LeeDepartment of Computer Science & Engineering, Yuan Ze University, Taoyuan, Taiwan.
Kai-Yao HuangWarshel Institute for Computational Biology, Chinese University of Hong Kong, Shenzhen, China.
Hsiao-Chen NingDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Nan-Chang LaiDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Ming-Hsiu TsaiGraduate Institute of Technological and Vocational Education, National Taipei University of Technology, Taipei, Taiwan.
Li-Chuan LuDepartment of Pathology, National Defense Medical Center, Division of Clinical Pathology, Tri-Service General Hospital, Taipei, Taiwan.
Yi-Ju TsengDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. yjtseng@mail.cgu.edu.tw.ORCID http://orcid.org/0000-0002-1814-5553
Jang-Jih LuDepartment of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. janglu45@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichomonas vaginalis (T. vaginalis) detection remains an unsolved problem in using of automated instruments for urinalysis. The study proposes a machine learning (ML)-based strategy to increase the detection rate of T. vaginalis in urine. On the basis of urinalysis data from a teaching hospital during 2009-2013, individuals underwent at least one urinalysis test were included. Logistic regression, support vector machine, and random forest, were used to select specimens with a high risk of T. vaginalis infection for confirmation through microscopic examinations. A total of 410,952 and 428,203 specimens from men and women were tested, of which 91 (0.02%) and 517 (0.12%) T. vaginalis-positive specimens were reported, respectively. The prediction models of T. vaginalis infection attained an area under the receiver operating characteristic curve of more than 0.87 for women and 0.83 for men. The Lift values of the top 5% risky specimens were above eight. While the most risky vigintile was picked out by the models and confirmed by microscopic examination, the incremental cost-effectiveness ratios for T. vaginalis detection in men and women were USD$170.1 and USD$29.7, respectively. On the basis of urinalysis, the proposed strategy can significantly increase the detection rate of T. vaginalis in a cost-effective manner.

Indexed as

Diagnosis, Computer-AssistedMachine LearningTrichomonas vaginalisUrinalysisAdultArea Under CurveCost-Benefit AnalysisFemaleHumansMaleMiddle AgedModels, TheoreticalPattern Recognition, AutomatedRetrospective StudiesROC CurveSex Factors

Identifiers

PMID31423009
PMCPMC6698480

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.