ArticleCurrent biology : CB2019
Large-Scale Communication in the Human Brain Is Rhythmically Modulated through Alpha Coherence.
Article in Current biology : CB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.
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Who cites it
73 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- EEG biomarkers for assessment, prognosis, and monitoring of natural upper limb recovery after stroke: a systematic review.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Functional and effective EEG connectivity patterns in Alzheimer's disease and mild cognitive impairment: a systematic review.Frontiers in aging neuroscience · 2025Pooled it
- Towards Network-Based Neurofeedback of Visual Areas to Enhance Visual Perception.Brain topography · 2026Trial
- Early High-Frequency Network Reorganization After Spinal Cord Stimulation Is Linked to Long-Term Recovery in Disorders of Consciousness.CNS neuroscience & therapeutics · 2026Article
- Alterations in Early Alpha-band Connectivity emerge in Infancy among children later diagnosed with Autism.medRxiv : the preprint server for health sciences · 2026Article
- Thermodynamic rigidity of harmonic brain states relates to general mental ability in juvenile myoclonic epilepsy.bioRxiv : the preprint server for biology · 2026Article
- Respiration as a dynamic modulator of sensory sampling.Nature communications · 2026Article
- Misinterpreting Electrophysiology in Human Cognitive Neuroscience.Psychophysiology · 2026Review
- A Spatially Structured Spiking Network Model of Beta Traveling Waves and Their Attenuation in Motor Cortex.bioRxiv : the preprint server for biology · 2026Article
- Pulse waveform and current direction alter network-level TMS-induced functional connectivity: Evidence from TMS-EEG.NeuroImage · 2026Article
- Number of Alpha Peaks in the Electroencephalogram Is Associated With Clinical Phenotype and Copy Number Variants in Youths With Autism.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Reduced cortical excitability is associated with head impact severity and cognitive symptoms in adolescent football players.iScience · 2026Article
- High-frequency bursts facilitate fast communication for human spatial attention.Nature neuroscience · 2026Article
- Income insufficiency impacts early brain development in infants facing increased psychosocial adversity: A network-based approach.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- High-density EEG network analysis in MCI: an exploratory study of electrode density and cognitive performance.Frontiers in aging neuroscience · 2026Article
- Modulation of EEG Background Rhythms in Sturge-Weber Syndrome: Impact of Surgical Timing on the Unaffected Hemisphere.Journal of central nervous system disease · 2026Article
- Evaluating oscillatory mechanisms underlying flexible neural communication in the human brain.Network neuroscience (Cambridge, Mass.) · 2026Article
- Modeling Working Memory in Neurodegeneration: A Focus on EEG Methods.Diagnostics (Basel, Switzerland) · 2025Review
- Probabilistic inference of social presence across brain scales reveals enhanced synaptic efficacy.Communications biology · 2025Article
- Evaluating oscillatory mechanisms underlying flexible neural communication in the human brain.bioRxiv : the preprint server for biology · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Recent evidence has suggested that coherent neuronal oscillations may serve as a gating mechanism for flexibly modulating communication between brain regions. For this to occur, such oscillations should be robust and coherent between brain regions that also demonstrate time-locked correlations, with time delays that match the phase delays of the coherent oscillations. Here, by analyzing functional connectivity in both the time and frequency domains, we demonstrate that alpha oscillations satisfy these constraints and are well suited for modulating communication over large spatial scales in the human brain. We examine intracranial EEG in the human temporal lobe and find robust alpha oscillations that are coherent between brain regions with center frequencies that are consistent within each individual participant. Regions demonstrating coherent narrowband oscillations also exhibit time-locked broadband correlations with a consistent time delay, a requirement for an efficient communication channel. The phase delays of the coherent alpha oscillations match the time delays of the correlated components, and importantly, both broadband correlations and neuronal spiking activity are modulated by the phase of the oscillations. These results are specific to the alpha band and build upon emerging evidence suggesting that alpha oscillations may play an active role in cortical function. Our data therefore provide evidence that large-scale communication in the human brain may be rhythmically modulated by alpha oscillations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.