Evidence map›Paper›PMID 31422284›Full record

ArticleiScience2019

Commensal Gut Bacteria Buffer the Impact of Host Genetic Variants on Drosophila Developmental Traits under Nutritional Stress.

Dali Ma, Maroun Bou-Sleiman, Pauline Joncour, Claire-Emmanuelle Indelicato, Michael Frochaux, Virginie Braman, Maria Litovchenko, Gilles Storelli, Bart Deplancke, François Leulier

Open access · goldAbstract read
In one paragraph

Article in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Is it time to assignApplied and environmental microbiology · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. How gut microbiome interactions affect nutritional traits ofThe Journal of experimental biology · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Dali MaInstitut de Génomique Fonctionnelle de Lyon (IGFL), Université de Lyon, Ecole Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Université Claude Bernard Lyon 1, Unité Mixte de Recherche 5242, 69364 Cedex 07, Lyon, France.
Maroun Bou-SleimanLaboratory of Systems Biology and Genetics, Institute of Bioengineering and Swiss Institute of Bioinformatics, School of Life Sciences Ecole Polytechnique Federale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
Pauline JoncourInstitut de Génomique Fonctionnelle de Lyon (IGFL), Université de Lyon, Ecole Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Université Claude Bernard Lyon 1, Unité Mixte de Recherche 5242, 69364 Cedex 07, Lyon, France.
Claire-Emmanuelle IndelicatoInstitut de Génomique Fonctionnelle de Lyon (IGFL), Université de Lyon, Ecole Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Université Claude Bernard Lyon 1, Unité Mixte de Recherche 5242, 69364 Cedex 07, Lyon, France.
Michael FrochauxLaboratory of Systems Biology and Genetics, Institute of Bioengineering and Swiss Institute of Bioinformatics, School of Life Sciences Ecole Polytechnique Federale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
Virginie BramanLaboratory of Systems Biology and Genetics, Institute of Bioengineering and Swiss Institute of Bioinformatics, School of Life Sciences Ecole Polytechnique Federale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
Maria LitovchenkoLaboratory of Systems Biology and Genetics, Institute of Bioengineering and Swiss Institute of Bioinformatics, School of Life Sciences Ecole Polytechnique Federale de Lausanne (EPFL), 1015, Lausanne, Switzerland.
Gilles StorelliInstitut de Génomique Fonctionnelle de Lyon (IGFL), Université de Lyon, Ecole Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Université Claude Bernard Lyon 1, Unité Mixte de Recherche 5242, 69364 Cedex 07, Lyon, France.
Bart DeplanckeLaboratory of Systems Biology and Genetics, Institute of Bioengineering and Swiss Institute of Bioinformatics, School of Life Sciences Ecole Polytechnique Federale de Lausanne (EPFL), 1015, Lausanne, Switzerland. Electronic address: bart.deplancke@epfl.ch.
François LeulierInstitut de Génomique Fonctionnelle de Lyon (IGFL), Université de Lyon, Ecole Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Université Claude Bernard Lyon 1, Unité Mixte de Recherche 5242, 69364 Cedex 07, Lyon, France. Electronic address: francois.leulier@ens-lyon.fr.
SIB Swiss Institute of Bioinformatics · CHInstitut de Génomique Fonctionnelle de Lyon · FRÉcole Normale Supérieure de Lyon · FRÉcole Polytechnique Fédérale de Lausanne · CHUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotic genomes encode several buffering mechanisms that robustly maintain invariant phenotypic outcome despite fluctuating environmental conditions. Here we show that the Drosophila gut-associated commensals, represented by a single facultative symbiont, Lactobacillus plantarum (Lp

Indexed as

Biological SciencesMicrobiologyOral Microbiology

Identifiers

PMID31422284
PMCPMC6704380
OpenAlexW2966172189

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.