ArticleJACC. Cardiovascular imaging2020
Intravascular Polarimetry in Patients With Coronary Artery Disease.
Article in JACC. Cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Retardance2Retardance: unsupervised denoising for polarization-sensitive optical coherence tomography.Biomedical optics express · 2026Article
- Local Birefringence Imaging by Similar Mueller Matrix Averaging Method in Catheter-Based Polarization-Sensitive Optical Coherence Tomography.Chemical & biomedical imaging · 2026Article
- Polarization-sensitive optical coherence tomography-based fully-automated volumetric coronary fibrous cap characterization.European heart journal. Imaging methods and practice · 2026Article
- Modern Imaging Techniques for Percutaneous Coronary Intervention Guidance: A Focus on Intravascular Ultrasound and Optical Coherence Tomography.Journal of clinical medicine · 2025Review
- Intravascular imaging for acute coronary syndrome.NPJ cardiovascular health · 2025Review
- Unlocking the Secrets of Acute Coronary Syndromes Using Intravascular Imaging: From Pathophysiology to Improving Outcomes.Journal of clinical medicine · 2024Review
- Aging of deep venous thrombosisBiomedical optics express · 2024Article
- Estimation of Medium Depolarization Index with Noise Immunity in Catheter-Based PS-OCT toward Vascular Plaques Detection.Chemical & biomedical imaging · 2024Article
- Dual modality intravascular catheter system combining pulse-sampling fluorescence lifetime imaging and polarization-sensitive optical coherence tomography.Biomedical optics express · 2024Article
- Segmentation of anatomical layers and imaging artifacts in intravascular polarization sensitive optical coherence tomography using attending physician and boundary cardinality losses.Biomedical optics express · 2024Article
- Novel imaging modalities for the identification of vulnerable plaques.Frontiers in cardiovascular medicine · 2024Review
- Single-input polarization-sensitive optical coherence tomography through a catheter.Biomedical optics express · 2023Article
- Accuracy and limitation of plaque detection by coronary CTA: a section-to-section comparison with optical coherence tomography.Scientific reports · 2023Article
- Role of plaque imaging for identification of vulnerable patients beyond the stage of myocardial ischemia.Frontiers in cardiovascular medicine · 2023Review
- Endoscopic imaging of white matter fiber tracts using polarization-sensitive optical coherence tomography.NeuroImage · 2022Article
- Unravelling the role of macrophages in cardiovascular inflammation through imaging: a state-of-the-art review.European heart journal. Cardiovascular Imaging · 2022Review
- Individual and joint effects of borderline ankle-brachial index and high plasma total homocysteine on all-cause death in hypertensive adults.Journal of geriatric cardiology : JGC · 2022Article
- Determinants of Non-calcified Low-Attenuation Coronary Plaque Burden in Patients Without Known Coronary Artery Disease: A Coronary CT Angiography Study.Frontiers in cardiovascular medicine · 2022Article
- Carotid Artery Stiffness: Imaging Techniques and Impact on Cerebrovascular Disease.Frontiers in cardiovascular medicine · 2022Review
- Newer-Generation Drug-Eluting Stents in Patients Undergoing Complex Percutaneous Coronary Intervention.JACC. Asia · 2021Article
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Abstract
objectivesThe aims of this first-in-human pilot study of intravascular polarimetry were to investigate polarization properties of coronary plaques in patients and to examine the relationship of these features with established structural characteristics available to conventional optical frequency domain imaging (OFDI) and with clinical presentation.
backgroundPolarization-sensitive OFDI measures birefringence and depolarization of tissue together with conventional cross-sectional optical frequency domain images of subsurface microstructure.
methodsThirty patients undergoing polarization-sensitive OFDI (acute coronary syndrome, n = 12; stable angina pectoris, n = 18) participated in this study. Three hundred forty-two cross-sectional images evenly distributed along all imaged coronary arteries were classified into 1 of 7 plaque categories according to conventional OFDI. Polarization features averaged over the entire intimal area of each cross section were compared among plaque types and with structural parameters. Furthermore, the polarization properties in cross sections (n = 244) of the fibrous caps of acute coronary syndrome and stable angina pectoris culprit lesions were assessed and compared with structural features using a generalized linear model.
resultsThe median birefringence and depolarization showed statistically significant differences among plaque types (p < 0.001 for both, one-way analysis of variance). Depolarization differed significantly among individual plaque types (p < 0.05), except between normal arteries and fibrous plaques and between fibrofatty and fibrocalcified plaques. Caps of acute coronary syndrome lesions and ruptured caps exhibited lower birefringence than caps of stable angina pectoris lesions (p < 0.01). In addition to clinical presentation, cap birefringence was also associated with macrophage accumulation as assessed using normalized SD.
conclusionsIntravascular polarimetry provides quantitative metrics that help characterize coronary arterial tissues and may offer refined insight into coronary arterial atherosclerotic lesions in patients.
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